3 documents found, page 1 of 1
Omega-3 fatty acids : possible ceuroprotective mechanisms in the model of globa...
Nobre, Maria Elizabeth Pereira; Correia, Alyne Oliveira; Mendonça, Francisco Nilson Maciel; Uchoa, Luiz Ricardo AraújoBackground. Omega-3 (3) administration was shown to protect against hypoxic-ischemic injury. The objectives were to study the neuroprotective effects of 3, in a model of global ischemia. Methods. Male Wistar rats were subjected to carotid occlusion (30 min), followed by reperfusion. The groups were SO, untreated ischemic and ischemic treated rats with 3 (5 and 10 mg/kg, 7 days). The SO and untreated ischemic an...
Aspectos toxicológicos da Benzidamina
Callou, Iana Bantim Felicio; Siqueira, Rafaelly Maria Pinheiro; Carvalho, Mailson Fontes de; Freitas, Ana Paula Fragoso de; Mariz, Saulo RiosThe drug abuse has been the object of several research. Among these substances, the benzydamine is widely used as an anti-inflammatory and as a drug of abuse. We conducted a literature review about the "toxicological aspects of benzydamine”, focusing on clinical issues, both with regard to therapeutic effects as toxic aspects. A literature review was conducted through the databases Pubmed, Scielo, Lilacs and Me...
Avaliação do efeito neuroprotetor da Pentoxifilina em modelos de convulsão indu...
Siqueira, Rafaelly Maria PinheiroEpilepsy is considered one of the most important brain diseases in all whole world and its prevalence reaches 5%. Pilocarpine (P400) is a cholinergic agonist which is characterized by its capacity to induce seizures that evolutes to status epilepticus similar to human temporal lobus epilepsy. Pentylenetetrazole is a GABA antagonist that imitates the absence seizures and tonic-clonic seizures in humans. In this ...