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CCR5 chemokine receptor gene polymorphisms in ocular toxoplasmosis
de Faria Junior, Geraldo M.; Ayo, Christiane M.; de Oliveira, Amanda P.; Lopes, Alessandro G. [UNESP]; Frederico, Fábio B.Made available in DSpace on 2018-12-11T17:16:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-02-01; C–C chemokine receptor type 5 (CCR5) is a chemokine receptor that influences the immune response to infectious and parasitic diseases. This study aimed to determine whether the CCR5Δ32 and CCR5 59029 A/G polymorphisms are associated with the development of ocular toxoplasmosis in humans. Patients with p...
Low toxicity and favorable clinical and quality of life impact after non-myeloa...
Ruiz, Milton Artur [UNESP]; Kaiser, Roberto Luiz; De Quadros, Luiz Gustavo; Piron-Ruiz, Lilian; Peña-Arciniegas, TatianaMade available in DSpace on 2018-12-11T16:49:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-10-06; Objective: The incidence of adverse events in myeloablative transplant protocols is high in refractory Crohn's disease; this study used low doses of cyclophosphamide. Fourteen patients were submitted to non-myeloablative autologous hematopoietic stem cell transplantation. Results: The average number of ...
Intravitreal use of bone marrow mononuclear fraction containing CD34+ stem cell...
Siqueira, Rubens Camargo
Implants as drug delivery devices for the treatment of eye diseases
Silva, Gisele Rodrigues da; Fialho, Sílvia Ligório; Siqueira, Rubens Camargo; Jorge, Rodrigo; Cunha Júnior, Armando da SilvaThe treatment of diseases affecting the posterior segment of the eye is limited by the difficulty in transporting effective doses of drugs to the vitreous, retina, and choroid. Topically applied drugs are poorly absorbed due to the low permeability of the external ocular tissues and tearing. The blood-retina barrier limits drug diffusion from the systemic blood to the posterior segment, thus high doses of drug ...