4 documents found, page 1 of 1
Hepatitis B in the Northwestern region of Sao Paulo State: genotypes and resist...
Meneghello, Brígida Helena da Silva; Soares, Márcia Maria Costa Nunes; Silva, Vanessa Cristina Martins; Lemos, Marcilio FigueiredoIn Brazil, few studies on the molecular aspects of hepatitis B virus (HBV) infection have been conducted in the interior regions of Sao Paulo State. This study aimed to identify HBV genotypes and evaluate strains with resistance mutations for nucleoside analogues in the Administrative Region (AR) of the municipality of Sao Jose do Rio Preto. We performed nested PCRs of 127 samples from the Health Care Services ...
Heterogeneous phenotype of hereditary xerocytosis in association with PIEZO1 va...
Sitnik, Roberta
A real-time quantitative assay for hepatitis B DNA virus (HBV) developed to det...
Sitnik, Roberta; Paes, Ângela; Mangueira, Cristovão Pitangueira; Pinho, João Renato RebelloHepatitis B virus (HBV) is a major cause of chronic liver disease worldwide. Besides genotype, quantitative analysis of HBV infection is extensively used for monitoring disease progression and treatment. Affordable viral load monitoring is desirable in resource-limited settings and it has been already shown to be useful in developing countries for other viruses such as Hepatitis C virus (HCV) and HIV. In this p...
Simultaneous quantitation of serum HBV DNA and HBeAg can distinguish between sl...
Silva, Luiz Caetano da; Nova, Maria Luiza da; Ono-Nita, Suzane Kioko; Pinho, João Renato Rebello; Sitnik, Roberta; Santos, Vera Aparecida dosBACKGROUND: The quantitation of serum HBeAg is not commonly used to monitor viral response to therapy in chronic hepatitis B. METHODS: In this study, 21 patients receiving varying therapies were followed and their viral response monitored by concomitant viral load and HBeAg quantitation in order to study the meaning and the kinetics of both parameters. RESULTS: It was possible to distinguish between three diffe...