7 documents found, page 1 of 1
HBM4EU-MOM: Prenatal methylmercury-exposure control in five countries through s...
Katsonouri, Andromachi; Gabriel, Catherine; Esteban López, Marta; Namorado, Sónia; Halldorsson, Thorhallur; Snoj Tratnik, Janja; Rodriguez Martin, LauraBackground: Seafood is a major source of vital nutrients for optimal fetal growth, but at the same time is the main source of exposure to methylmercury (MeHg), an established neurodevelopmental toxicant. Pregnant women must be provided with dietary advice so as to include safely fish in their diet for nutrition and mercury control. The aim of this work is to present the design of a multicentre randomized contro...
Harmonized human biomonitoring in European children, teenagers and adults: EU-w...
Govarts, Eva; Gilles, Liese; Rodriguez Martin, Laura; Santonen, Tiina; Apel, Petra; Alvito, Paula; Anastasi, Elena; Andersen, Helle RaunAbstract: As one of the core elements of the European Human Biomonitoring Initiative (HBM4EU) a human biomonitoring (HBM) survey was conducted in 23 countries to generate EU-wide comparable HBM data. This survey has built on existing HBM capacity in Europe by aligning national or regional HBM studies, referred to as the HBM4EU Aligned Studies. The HBM4EU Aligned Studies included a total of 10,795 participants o...
Cadmium exposure in adults across Europe: Results from the HBM4EU Aligned Studi...
Snoj Tratnik, Janja; Kocman, David; Horvat, Milena; Andersson, Anna-Maria; Juul, Anders; Jacobsen, Eva; Olafsdottir, Kristin; Klanova, JanaThe objectives of the study were to estimate the current exposure to cadmium (Cd) in Europe, potential differences between the countries and geographic regions, determinants of exposure and to derive European exposure levels. The basis for this work was provided by the European Human Biomonitoring Initiative (HBM4EU) which established a framework for alignment of national or regional HBM studies. For the purpos...
A Tiered Approach for Assessing Individual and Combined Risk of Pyrethroids Usi...
Tarazona, Jose; Cattaneo, Irene; Niemann, Lars; Pedraza-Diaz, Susana; González-Caballero, MCarmen; Alba-Gonzalez, Mercedes de; Cañas, AnaPyrethroids are a major insecticide class, suitable for biomonitoring in humans. Due to similarities in structure and metabolic pathways, urinary metabolites are common to various active substances. A tiered approach is proposed for risk assessment. Tier I was a conservative screening for overall pyrethroid exposure, based on phenoxybenzoic acid metabolites. Subsequently, probabilistic approaches and more speci...
HBM4EU-MOM: intervene to raise awareness to specific dietary recommendations an...
Namorado, Sónia; Assunção, Ricardo; Santiago, Susana; Esteban López, Marta; Dominguez Morueco, Noelia; Ingi Halldórsson, Þórhallur; Jacobsen, EvaBACKGROUND AND AIM:Mercury and its compounds are toxic and are among the substances of higher concern globally.Toxicity depends on mercury compounds, route of exposure and duration. The European population is mostly exposed to organic mercury (methylmercury) due to fish consumption; while exposure to inorganic and elemental mercury is largely associated with dental amalgams, accidental spills of elemental mercu...
Towards harmonized biobanking for biomonitoring : a comparison of human biomoni...
Lermen, Dominik; Gwinner, Frederik; Bartel-Steinbach, Martina; Mueller, Sabine C.; Habermann, Jens K.; Balwir, Matharoo-Ball; Smits, ElkeHuman biomonitoring (HBM) depends on high-quality human samples to identify status and trends in exposure and ensure comparability of results. In this context, much effort has been put into the development of standardized processes and quality assurance for sampling and chemical analysis, while effects of sample storage and shipment on sample quality have been less thoroughly addressed. To characterize the curr...
First steps toward harmonized human biomonitoring in Europe : demonstration pro...
Den Hond, Elly; Govarts, Eva; Willems, Hanny; Smolders, Roel; Casteleyn, Ludwine; Kolossa-Gehring, Marike; Schwedler, Gerda; Seiwert, MargareteBackground: For Europe as a whole, data on internal exposure to environmental chemicals do not yet exist. Characterization of the internal individual chemical environment is expected to enhance understanding of the environmental threats to health. Objectives: We developed and applied a harmonized protocol to collect comparable human biomonitoring data all over Europe. Methods: In 17 European countries, we measu...