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Motivos de exclusão para a cirurgia de estimulação cerebral profunda na doença ...

Carvalho, Miguel de Oliveira; Cattoni, Maria Begoña; Guedes, Leonor Correia; Carvalho, Herculano; Lobo, Patricia Pita; Albuquerque, Luisa


Disability in activities of daily living and severity of dyskinesias determine ...

Coelho, Miguel; Abreu, Daisy; Correia-Guedes, Leonor; Lobo, Patrícia Pita; Fabbri, Margherita; Godinho, Catarina; Domingos, Josefa; Albuquerque, Luisa

"BACKGROUND: There is scarce data on the level of handicap in Parkinson's disease (PD) and none in advanced stage PD. OBJECTIVE: To assess the handicap in advanced stage PD patients with disabling levodopa-induced motor complications selected to deep brain stimulation (DBS). METHODS: Data was prospectively recorded during routine evaluation for DBS. Handicap was measured using London Handicap Scale (LHS) (0 = m...


Depression with melancholic features is associated with higher long-term risk f...

Simões Do Couto, Frederico; Lunet, Nuno; Ginó, Sandra; Chester, Catarina; Freitas, Vanda; Maruta, Carolina; Figueira, Maria Luísa

Background: Depression has been reported to increase the risk of subsequently developing dementia, but the nature of this relation remains to be elucidated. Depression can be a prodrome/manifestation of dementia or an early risk factor, and the effect may differ according to depression subtypes. Our aim was to study the association between early-onset depression and different depression subtypes, and the later ...


Avaliação do Estado Mental para Estimulação Cerebral Profunda: “ON” vs. “OFF”

Freitas, Vanda; Coelho, Miguel; Albuquerque, Luísa; Godinho, Catarina; Rosa, Mário Miguel; Martins, Isabel Pavão


The effect of education on age-related changes in three cognitive domains: a cr...

Martins, Isabel Pavão; Maruta, Carolina; Silva, Cláudia; Rodrigues, Pedro; Chester, Catarina; Ginó, Sandra; Freitas, Vanda; Freitas, Sara

The present study aims to investigate the protective effect of formal education on age-related changes in different cognitive domains with the hypothesis that it may attenuate the rate of decline. Individuals aged 50 years or older attending primary care physicians without known brain disease (431 participants, mostly [60.3%] female with 66.3 [±9.1] years of age and 7.7 [±4.1] years of education, on average), w...


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