3 documents found, page 1 of 1
In vitro studies on Bothrops venoms cytotoxic effect on tumor cells
Jorge, Roberta J. B.; Martins, Alice M. C.; Morais, Isabel C. O.; Ximenes, Rafael M.; Rodrigues, Felipe A. R.; Soares, Bruno M.Made available in DSpace on 2022-04-29T02:17:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-12-29; Background: Animal venoms are complex mixtures of proteins and non proteins components with several biological activities. Snake venoms represent an essentially unexplored source of bioactive compounds that may cure disease conditions which do not respond to currently available therapies. These venoms p...
Human papillomavirus genotype distribution among cervical cancer patients prior...
Almeida, Liz M. de; Martins, Luís Felipe L.; Pontes, Valéria B.; Corrêa, Flávia M.; Montenegro, Raquel C.; Pinto, Laine C.; Soares, Bruno M.To evaluate the impact of HPV immunization and possible changes in virus type-specific prevalence associated with cervical cancer, it is important to obtain baseline information based on socioeconomic, educational, and environmental characteristics in human populations. We describe these characteristics and the type-specific HPV distribution in 1,183 women diagnosed with cervical cancer in two Brazilian healthc...
Synthesis and cytotoxic evaluation of a series of 2-amino-naphthoquinones again...
Moraes, Thiago A. P. de; S. Filha, Maria J.; Camara, Celso A.; Silva, Tania M. S.; Soares, Bruno M.; Bomfim, Igor S.; Pessoa, ClaudiaThe cytotoxicity of a series of aminonaphthoquinones resulting from the reaction of suitable aminoacids with 1,4-naphthoquinone was assayed against SF-295 (glioblastoma), MDAMB-435 (breast), HCT-8 (colon), HCT-116 (colon), HL-60 (leukemia), OVCAR-8 (ovarian), NCI-H358M (bronchoalveolar lung carcinoma) and PC3-M (prostate) cancer cells and also against PBMC (peripheral blood mononuclear cells). The results demon...