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Evaluation of cytotoxic and antimicrobial effects of two Bt cry proteins on a G...

Farias, Davi Felipe; Viana, Martônio Ponte; Oliveira, Gustavo Ramos de; Beneventi, Magda Aparecida; Soares, BrunoMarques; Pessoa, Claudia

Studies have contested the innocuousness of Bacillus thuringiensis (Bt) Cry proteins to mammalian cells as well as to mammals microbiota.Thus, this study aimed to evaluate the cytotoxic and antimicrobial effects of two Cry proteins, Cry8Ka5 (a novelmutant protein) and Cry1Ac (a widely distributed protein in GM crops). Evaluation of cyto- and genotoxicity in human lymphocytes was performed as well as hemolytic a...

Date: 2014   |   Origin: Oasisbr
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