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Platelet-derived products in veterinary medicine: A new trend or an effective t...
Soares, Carla S.; Babo, Pedro Miguel Sousa; Reis, R. L.; Carvalho, P. P.; Gomes, Manuela E.Platelet-derived products (PDPs) have gained popularity, mainly due to their high concentrations of bioactive molecules such as growth factors and cytokines, which play important roles in tissue healing and regeneration. PDPs are obtained through minimally invasive procedures and their therapeutic effect has been widely recognized. In veterinary medicine, however, the lack of standard protocols to generate PDPs...
Bioengineered surgical repair of a chronic oronasal fistula in a cat using auto...
Soares, Carla S.; Barros, Luís C.; Saraiva, Virgínia; Gomez-Florit, Manuel; Babo, Pedro Miguel Sousa; Dias, Isabel R.; Reis, R. L.; Carvalho, Pedro P.Clinical summary: A tissue engineering approach was used to aid the surgical repair of a chronic oronasal fistula (ONF) in a 13-year-old cat. A three-dimensional (3D) printed mesh, tailored to the size and shape of the ONF, was created to support a soft tissue flap used to close the defect; and also to provide a matrix for mesenchymal stromal cells present in bone marrow aspirate and bioactive cytokines and gro...