7 documents found, page 1 of 1
Genetic Variants in PTGS1 and NOS3 Genes Increase the Risk of Upper Gastrointes...
Forgerini, Marcela [UNESP]; Urbano, Gustavo; Nadai, Tales Rubens de; Batah, Sabrina Setembre; Fabro, Alexandre TodorovicMade available in DSpace on 2022-04-29T08:30:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-07-05; Objective: To assess the association between PTGS1 and NOS3 variant alleles and the risk to develop upper gastrointestinal bleeding (UGIB) secondary to complicated peptic disease. Methods: A case–control study was conducted in a Brazilian complex hospital from July 2016 to March 2020. Case: Patients wit...
Heart remodeling produced by aortic stenosis promotes cardiomyocyte apoptosis m...
Sant'Ana, Paula Grippa [UNESP]; Batah, Sabrina Setembre; Leão, Patrícia Santos; Teodoro, Walcy Rosolia; de Souza, Sérgio Luiz Borges [UNESP]Made available in DSpace on 2022-04-29T08:27:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-01; Cardiac remodeling (CR) is a structural change of the heart due to chronic hemodynamic overload related to changes in both myocyte and extracellular matrix (ECM). We investigated that the imbalance of collagen V promotes cardiomyocyte apoptosis that contributes to heart failure and cell death. Aortic st...
Higher Concentration of Taenia Antigens in the CSF is Related to Slight Ventric...
Silva, Monica Almeida [UNESP]; Barcelos, Eduardo Vieira [UNESP]; Aves Junior, Aderaldo Costa [UNESP]; Generoso, Diego [UNESP]; Alda, Maiara AlmeidaMade available in DSpace on 2021-06-25T12:25:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-26; Purpose Experimental models might help understand the pathophysiology of neurocysticercosis-associated hydrocephalus. The present study aimed to compare the extent of hydrocephalus and tissue damage in rats with subarachnoid inoculation of different concentrations of Taenia crassiceps cyst proteins. Met...
Circulating Plasma miRNA and Clinical/Hemodynamic Characteristics Provide Addit...
Fabro, Alexandre Todorovic; Machado-Rugolo, Juliana [UNESP]; Baldavira, Camila Machado; Prieto, Tabatha Gutierrez; Farhat, CecíliaMade available in DSpace on 2021-06-25T11:02:25Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-05-28; Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ); Idiopathic pulmonary artery hypertension (IPAH), chronic thromboembolic pulmonary hypertension (CTEPH), and acute pulmonary embolism (APTE) are life-threatening cardiopulmonary diseases without specific surgical or medical treatment. Al...
In situ Evidence of Collagen V and Interleukin-6/Interleukin-17 Activation in V...
Batah, Sabrina Setembre; Alda, Maiara Almeida; Lopes Roslindo Figueira, Rebeca Rodrigues; Cruvinel, Heloisa R. [UNESP]Made available in DSpace on 2021-06-25T15:07:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01; Several studies have reported the pathophysiologic and molecular mechanisms responsible for pulmonary arterial hypertension (PAH). However, the in situ evidence of collagen V (Col V) and interleukin-17 (IL-17)/interleukin-6 (IL-6) activation in PAH has not been fully elucidated. We analyzed the effects ...
A Rat Model of Neurocysticercosis-Induced Hydrocephalus: Chronic Progressive Hy...
Hamamoto Filho, Pedro Tadao [UNESP]; Fogaroli, Marcelo Ortolani [UNESP]; Oliveira, Marcelo Augusto Chiantelli [UNESP]Made available in DSpace on 2020-12-12T01:39:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-01; Background: Hydrocephalus is the most common complication of extraparenchymal neurocysticercosis, combining obstructive and inflammatory mechanisms that impair cerebrospinal fluid circulation. Methods: We studied the long-term progression of neurocysticercosis-induced hydrocephalus in a rat model. We ge...
Adipose-derived stem cells and adipose-derived stem cell-conditioned medium mod...
Felix, Renato Goncalves [UNESP]; Carvalho Bovolato, Ana Livia [UNESP]; Cotrim, Ondina Silvia [UNESP]; Leao, Patricia dos Santos; Batah, Sabrina SetembreMade available in DSpace on 2020-12-11T22:20:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-03-01; National Council for Scientific and Technological Development; Foundation for the Support of Research of the State of Sao Paulo; Laboratories for Medical Research [LIMs], Hospital das Clinicas, University of Sao Paulo; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); The immunogenic ...