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Results of the Portuguese EQA program for molecular detection of SARS-CoV-2, in...

The initial strategy for containing the spread of SARS-CoV-2 was the prompt identification of COVID-19 cases, as recommended by the World Health Organization (WHO). These recommendations demanded an expansion of the laboratory capacity to implement the testing procedures to detect SARS-CoV-2. In March 2020, the Portuguese National External Quality Assessment Program (PNAEQ) with the collaboration of the Nationa...

Results of the Portuguese pilot EQA program in SARS-CoV-2, PCR

Introduction: Initial strategy for containing the spread of SARS CoV 2 was the prompt identification of COVID 19 cases, as recommended by the World Health Organization These recommendations demanded an expansion of the laboratory capacity to implement the testing procedures to detect SARS CoV 2. In March 2020 the Portuguese National External Quality Assessment Program ( with the National Reference Laboratory ( ...

Avaliação Externa da Qualidade - deteção do vírus influenza A e B, PNAEQ (2011-...

Os vírus influenza são responsáveis por infeções respiratórias que ocorrem de forma sazonal geralmente no inverno, ou como pandemias periódicas e imprevisíveis. As técnicas de diagnóstico/deteção molecular são métodos rápidos e sensíveis para a deteção e identificação de vírus influenza. Em 2011 o PNAEQ implementou o programa de avaliação externa da qualidade para os vírus influenza A e B deteção de ácido nucle...

Genetic variability of influenza virus and vaccine effectiveness

Euroeva is the portuguese component of the multicentric study I-MOVE (influenza monitoring vaccine effectiveness in Europe) that aims to estimate influenza vaccine effectiveness in Europe. As an higher vaccine effectiveness is expected when circulating viruses are similar to the vaccine strains, this study aims to describe circulating strains and amino acid substitutions in antigenic sites in order to better un...

Estimates of 2012/13 influenza vaccine effectiveness using the case test-negati...

Background: In recent years several reports of influenza vaccine effectiveness (VE) have been made early for public health decision. The majority of these studies use the case test-negative control design (TND),which has been showed to provide, under certain conditions, unbiased estimates of influenza VE. Nevertheless, discussions have been taken on the best influenza negative control group to use. The presents...

Identification of nontuberculous mycobacteria by partial gene sequence and publ...

Background: Nontuberculous mycobacteria (NTM) are a heterogeneous group of microorganisms with distinct clinical relevance. The treatment of NTM infections depends significantly upon the crucial identification of species at this level. The steady increase of mycobacteria species, the use of time-consuming techniques and the lack of standardized identification methods makes the achievement of this goal a demandi...

Doença meningocócica invasiva em Portugal - Vigilância epidemiológica de base l...

A doença meningocócica (DM), endémica em Portugal e em muitos países industrializados, constitui ainda hoje um grave problema de saúde pública devido à sua alta incidência em crianças menores de quatro anos, à taxa de letalidade e de sequelas graves. De notificação clínica obrigatória, a doença meningocócica passou a ter notificação laboratorial também obrigatória a partir de 2002, por implementação da Circular...

Vírus respiratórios e gripe entre 2010 e 2013, em Portugal