4 documents found, page 1 of 1
Using resting-state DMN effective connectivity to characterize the neurofunctio...
Esménio, Sofia; Soares, José M.; Oliveira-Silva, P.; Zeidman, Peter; Razi, Adeel; Gonçalves, Óscar F.; Coutinho, JoanaNeuroimaging studies in social neuroscience have largely relied on functional connectivity (FC) methods to characterize the functional integration between different brain regions. However, these methods have limited utility in social-cognitive studies that aim to understand the directed information flow among brain areas that underlies complex psychological processes. In this study we combined functional and ef...
Asymmetrical subcortical plasticity entails cognitive progression in older indi...
Esteves, Madalena; Moreira, Pedro S.; Marques, Paulo; Castanho, Teresa Jesus Costa; Magalhães, Ricardo; Amorim, Liliana Patrícia CarvalhoStructural brain asymmetries have been associated with cognition. However, it is not known to what extent neuropsychological parameters and structural laterality covary with aging. Seventy-five subjects drawn from a larger normal aging cohort were evaluated in terms of MRI and neuropsychological parameters at two moments (M1 and M2), 18 months apart. In this time frame, asymmetry as measured by structural later...
Functional Hemispheric (A)symmetries in the Aged Brain-Relevance for Working Me...
Esteves, Madalena; Magalhães, Ricardo José Silva; Marques, Paulo; Castanho, Teresa Jesus Costa; Portugal-Nunes, Carlos; Soares, José M.Functional hemispheric asymmetries have been described in different cognitive processes, such as decision-making and motivation. Variations in the pattern of left/right activity have been associated with normal brain functioning, and with neuropsychiatric diseases. Such asymmetries in brain activity evolve throughout life and are thought to decrease with aging, but clear associations with cognitive function hav...
Evaluating performance on older individuals using a fMRI protocol for Wisconsin...
Festa, Joana Araújo; Soares, José M.; Marques, Paulo; Santos, Nadine Correia; Sousa, Nuno; Dias, NunoThis paper describes an fMRI study with 76 middle-aged and older subjects using the Wisconsin Card Sorting Task, widely utilized to investigate executive function and frontal lobe dysfunction. Several cognitive processes involved in the task are correlated with the cognitive decline observed due to aging. With functional imaging we demonstrate that subjects with a better performance show an increased activation...