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Immunosensor for pancreatic cancer based on electrospun nanofibers coated with ...

Soares, Juliana C.; Iwaki, Leonardo E. O.; Soares, Andrey C.; Rodrigues, Valquiria C.; Melendez, Matias Eliseo; Fregnani, José Humberto T. G.

We report the fabrication of immunosensors based on nanostructured mats of electrospun nanofibers of polyamide 6 and poly(allylamine hydrochloride) coated either with multiwalled carbon nanotubes (MWCNTs) or gold nanoparticles (AuNPs), whose three-dimensional structure was suitable for the immobilization of anti-CA19-9 antibodies to detect the pancreatic cancer biomarker CA19-9. Using impedance spectroscopy, th...


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