3 documents found, page 1 of 1
Field validation of a Leishmania (Leishmania) mexicana exo-antigens ELISA for d...
Soares, Killarney Ataide; Urdapilleta, Ada Amália Ayala; Santos, Gilcilene Maria dos; Carneiro, Andréa Lisboa; Gomes, Ciro Martins; Roselino, Ana MariaBackground: several tests are performed to obtain better accuracy when diagnosing American tegumentary leishmaniasis (ATL). It is believed that antigens released via secretion, excretion and metabolism are more specific than are antigens released by the lysis of Leishmaniaparasites. Such antigens are known as exo-antigens (exo-Ag) and are formed from products released by cultured parasites in a way that is simi...
Validação doTeste de Elisa com exoantígenos e da imunofluorescência direta para...
Soares, Killarney AtaideTese (doutorado)—Universidade de Brasília, Programa de Pós-Graduação em Ciências Médicas, 2011.; A leishmaniose tegumentar americana (LTA) é um problema de saúde pública, cujo diagnóstico depende dos diversos métodos empregados em conjunto, na busca de obter melhor sensibilidade e especificidade. O objetivo do presente estudo foi validar a técnica de ELISA empregando exoantígenos (ELISA exoAg) de Leishmania mex...
The dog as model for chemotherapy of the Chagas’ disease.
Guedes, Paulo Marcos da Matta; Veloso, Vanja Maria; Tafuri, Washington Luiz; Galvão, Lúcia Maria da Cunha; Carneiro, Cláudia Martins; Lana, Marta deIn the present study, we investigated the role of dogs as experimental models for acute and chronic phases of Chagas’ disease, before and after therapeutic treatments. Dogs were infected with Trypanosoma cruzi strains of different susceptibilities to benznidazole (Bz) and treated with the same therapeutic scheme as used for human chagasic. The treatment with Bz was able to prevent death and induced parasitologi...