7 documents found, page 1 of 1

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Combined nandrolone and resistance training induced cardiac remodelling and oxi...

Moraes, Alexa Alves de; Suarez, Pedro Zavagli; Quintão, Arthur Eduardo de Carvalho; Fontes, Beatriz Lana; Costa, Sebastião Felipe Ferreira

Nandrolone decanoate (ND) is widely used by individuals engaged in resistance training (RT), yet their combined effects on cardiac function remain unclear. Objective To investigate the effects of RT and ND on cardiac structure and function, cellular contractility, Ca-2 (+) -handling protein expression, and redox balance in rats. Methods Thirty-two male Wistar rats were assigned to four groups: control (C), trai...

Date: 2026   |   Origin: Biblioteca Digital do IPB

Resistance Training Before Hyperalgesia Induction Promotes Analgesic Effects Th...

Chiapeta, Andrês Valente; Oliveira, Leandro Licursi; Leite, Luciano Bernardes; Silva, Bruna Aparecida Fonseca da; Costa, Sebastião Felipe Ferreira

Fibromyalgia is a chronic syndrome characterized by widespread pain and complex pathophysiology, requiring new therapeutic approaches. This study aims to investigate the effects of resistance training (RT) before hyperalgesia induction on pain sensitivity, IL-6 and IL-10 expression in skeletal muscle, and thalamic serotonin levels in a fibromyalgia (FM)-like rat model. Methods: Wistar female rats aged 12 months...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Blueberry Extract and Resistance Training Prevent Left Ventricular Redox Dysreg...

Leite, Luciano Bernardes; Soares, Leôncio Lopes; Guimarães-Ervilha, Luiz Otávio; Costa, Sebastião Felipe Ferreira; Generoso, Sara Caco dos Lúcio

To investigate whether the regular administration of blueberry extract and low-intensity resistance exercise training (RT), either alone or in combination, during the development of monocrotaline (MCT)-induced severe pulmonary arterial hypertension (PAH) in rats protect the left ventricle (LV) from redox dysregulation and pathological remodeling. Groups of seven male Wistar rats were formed for the experiment: ...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Combined exercise hinders the progression of pulmonary and right heart harmful ...

Leite, Luciano Bernardes; Soares, Leôncio Lopes; Portes, Alexandre Martins Oliveira; Silva, Bruna Aparecida Fonseca da; Dias, Taís Rodrigues

The aim of this study was to test whether combined physical exercise training of moderate intensity executed during the devel- opment of monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH) hinders the progression of pulmonary and right heart harmful functional and structural remodeling in rats. Wistar rats were injected with MCT (60 mg/kg) and after 24 h were exposed to a combined exercise trainin...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Effects of Tryptophan and Physical Exercise on the Modulation of Mechanical Hyp...

Rezende, Rafael Marins; Coimbra, Roney Santos; Kohlhoff, Markus; Favarato, Lukiya Silva Campos; Martino, Hércia Stampini Duarte

Though the mechanisms are not fully understood, tryptophan (Trp) and physical exercise seem to regulate mechanical hypersensitivity in fibromyalgia. Here, we tested the impact of Trp supplementation and continuous low-intensity aerobic exercise on the modulation of mechanical hypersensitivity in a fibromyalgia-like model induced by acid saline in female rats. Twelve-month-old femaleWistar rats were randomly div...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Effects of aerobic exercise on the inflammatory cytokine profile and expression...

Rodrigues, Aurora Corrêa; Leal, Tiago Ferreira; Costa, Alexandre Jayme Lopes Dantas; Silva, Franciany de Jesus; Soares, Leôncio Lopes

Investigate the effects of moderate continuous aerobic exercise (MCAE) on the inflammatory cytokine profile and expression of lipolytic and thermogenic genes in β1-AR−/− mice adipose tissue. Four- to five-month-old male wild type (WT) and β1-AR−/− mice were divided into groups: WT control (WTc) and trained (WTt); and β1-AR−/− control (β1-AR−/−c) and trained (β1-AR−/−t). Animals from trained groups were submitte...

Date: 2019   |   Origin: Oasisbr

Efeitos do treinamento físico sobre a estrutura e a função contrátil de cardiom...

Soares, Leôncio Lopes

O objetivo geral desta dissertação foi examinar os efeitos do treinamento físico sobre a estrutura e a função do miocárdio e sobre a função contrátil e o Ca 2+ intracelular transiente de cardiomiocitos do ventrículo direito em ratos com hipertensão arterial pulmonar (HAP) induzida por monocrotalina (MCT). O primeiro capítulo trata de uma revisão sistemática para examinar as adaptações funcionais e estruturais d...

Date: 2018   |   Origin: Oasisbr

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