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Perinatal Renal Vein Thrombosis: Role of Imaging in the Initial Diagnosis

Forjaco Jorge, AF; Riesenberger, PR; Soares, ME

We report the case of a neonate who presented with a left abdominal flank mass and hemodynamic instability signs, with the final diagnosis of left renal vein thrombosis complicated with inferior vena cava thrombosis and perirenal hematoma. We illustrate the importance of an early imaging approach with ultrasound and Doppler evaluation to finally diagnose perinatal renal vein thrombosis and its complications. Te...


d-Amphetamine-induced hepatoxicity: Possible contribution of catecholamines and...

Carvalho, F; Remiao, F; Soares, ME; Catarino, R; Queiroz, G; Bastos, ML

Amphetamines are indirect-acting sympathomimetic drugs widely abused due to their physical and psychostimulating effects. However, the use of these drugs has been associated with numerous reports of hepatotoxicity. While glutathione depletion induced by amphetamines contributes to the exposure of hepatocytes to oxidative damage, other indirect effects attributed to amphetamines may have a role in cell injury. T...


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