5 documents found, page 1 of 1
Design and synthesis of new Benzophenone derivatives with in vivo anti-inflamma...
Santos, Marcelo H. dos; Januario, Jaqueline P.; Souza, Thiago B. de; Lavorato, Stefânia N.; Maiolini, Tatiane C. S.; Domingos, Olívia S.A series of novel benzophenone derivatives containing a thiazole heterocyclic nucleus were designed by molecular hybridization. Molecular docking studies have demonstrated the inhibitory potential of the designed compounds against cyclooxygenase (COX) isoenzymes. These compounds were synthesized, characterized, and evaluated for their anti-inflammatory properties by the croton oil-induced ear edema assay to exa...
A Comparative Study on Chemical Composition, Antileishmanial and Cytotoxic Acti...
Oliveira, Emerson A.; Martins, Euder G. A.; Soares, Marisi G.; Chagas-Paula, Daniela A.; Passero, Luiz F. D. [UNESP]; Sartorelli, PatriciaMade available in DSpace on 2019-10-04T12:39:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-07-01. Added 1 bitstream(s) on 2019-10-09T18:34:14Z : No. of bitstreams: 1 S0103-50532019000701395.pdf: 3719551 bytes, checksum: 45f4a75da9350b6e921bbf6e4abc2ad3 (MD5); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenaç...
In vitro trypanocidal evaluation of pinane derivatives from essential oils of r...
Sartorelli, Patricia; Santana, Jefferson S.; Guadagnin, Rafael C.; Lago, João Henrique G.; Pinto, Érika G.; Tempone, André G.; Stefani, Hélio A.Essential oils of ripe fruits from Schinus terebinthifolius (Anacardiaceae), obtained using a pilot extractor and a Clevenger apparatus were chemically characterized. Due the high amount of (-)- α-pinene in both oils, this monoterpene was tested against the protozoan parasite Trypanosoma cruzi, showing a moderate potential (IC50 63.56 µg/mL) when compared to benznidazole (IC50 43.14 µg/mL). Otherwise, (-)- α-pi...
Assessing the chemical composition and antimicrobial activity of essential oils...
Santos, Nara O. dos; Mariane, Bruna; Lago, João Henrique G.; Sartorelli, Patricia; Rosa, Welton; Soares, Marisi G.; Silva, Adalberto M. daThe chemical composition and antimicrobial activity of essential oils obtained from three Brazilian plant species—leaves and branches of Eremanthus erythropappus (Asteraceae), leaves of Plectranthus barbatus, and leaves of P. amboinicus (Lamiaceae)—were determined. Analysis by GC/MS and determination of Kovats indexes both indicated δ-elemene (leaves—42.61% and branches—23.41%) as well as (−)-α-bisabolol (leave...
Volatile oil from Guarea macrophylla ssp. tuberculata: Seasonal variation and e...
Roque, Nídia Franca; Lago, João Henrique G.; Soares, Marisi G.; Pereira, Luciane G. Batista-; Silva, M. Fátima G. F.; Corrêa, Arlene G.Texto completo: acesso restrito. p.589–594; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2013-08-28T15:22:08Z No. of bitstreams: 1 1-s2.0-S0031942205007120-main.pdf: 209985 bytes, checksum: 45df5367e16f3c04ab2714b0b2fbd214 (MD5); Made available in DSpace on 2013-08-28T15:22:08Z (GMT). No. of bitstreams: 1 1-s2.0-S0031942205007120-main.pdf: 209985 bytes, checksum: 45df5367e16f3c04ab2714b0b2fbd214 (MD5...