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Predictive Ability of Cardiopulmonary Exercise Test Parameters in Heart Failure...

Ferreira Reis, J; Valentim Gonçalves, A; Garcia Brás, P; Ilhão Moreira, R; Rio, P; Timóteo, AT; Soares, RM; Cruz Ferreira, R

Background: There is evidence suggesting that a peak oxygen uptake (pVO2) cut-off of 10ml/kg/min provides a more precise risk stratification in cardiac resynchronization therapy (CRT) patients. Objective: To compare the prognostic power of several cardiopulmonary exercise testing (CPET) parameters in this population and assess the discriminative ability of the guideline-recommended pVO2cut-off values. Methods: ...


The Prognostic Value of the Cardiorespiratory Optimal Point During Submaximal E...

Ferreira Reis, J; Valentim Gonçalves, A; Brás, P; Moreira, R; Pereira-da-Silva, T; Timóteo, AT; Soares, RM; Cruz Ferreira, R

Introduction: Peak oxygen consumption (pVO2) is a key parameter for assessing the prognosis of heart failure with reduced ejection fraction (HFrEF). However, it is less reliable when the cardiopulmonary exercise test (CPET) is not maximal. Objective: To compare the prognostic power of various exercise parameters in submaximal CPET. Methods: Adult patients with HFrEF undergoing CPET in a tertiary center were pro...


Maximal Oxygen Uptake and Ventilation Improvement Following Sacubitril-Valsarta...

Valentim Gonçalves, A; Pereira-da-Silva, T; Galrinho, A; Rio, P; Soares, RM; Feliciano, J; Ilhão Moreira, R; Silva, S; Alves, S; Capilé, E

Background: Sacubitril/valsartan had its prognosis benefit confirmed in the PARADIGM-HF trial. However, data on cardiopulmonary exercise testing (CPET) changes with sacubitril-valsartan therapy are scarce. Objective: This study aimed to compare CPET parameters before and after sacubitril-valsartan therapy. Methods: Prospective evaluation of chronic heart failure (HF) patients with left ventricular ejection frac...


Impact of Cardiorespiratory Fitness on the Obesity Paradox in Heart Failure wit...

Ilhão Moreira, R; Pereira da Silva, T; Valentim Gonçalves, A; Feliciano, J; Rio, P; Soares, RM; Cruz Ferreira, R

Background: Higher body mass index (BMI) has been associated with improved outcomes in heart failure with reduced ejection fraction. This finding has led to the concept of the obesity paradox. Objective: To investigate the impact of exercise tolerance and cardiorespiratory capacity on the obesity paradox. Methods: Outpatients with symptomatic heart failure and left ventricular ejection fraction (LVEF) ≤ 40%, fo...


Unidades de Insuficiência Cardíaca: Estado da Arte na Abordagem da Insuficiênci...

Timóteo, AT; Pereira da Silva, T; Ilhão Moreira, R; Gonçalves, A; Soares, RM; Cruz Ferreira, R

The prevalence of heart failure has increased over the past decades and is a major social and economic burden on healthcare services. Patient quality of life is severely impaired and heart failure is one of the main causes of death in Portugal. The functional organization of multidisciplinary teams engaged in the treatment of these patients is essential to improve health care provision and outcomes, specificall...


Congenital Heart Disease in Adults: Assessment of Functional Capacity Using Car...

Aguiar Rosa, S; Agapito, A; Soares, RM; Sousa, L; Oliveira, JA; Abreu, A; Silva, AS; Alves, S; Aidos, H; Pinto, MF; Cruz Ferreira, R

AIM: The aim of the study was to compare functional capacity in different types of congenital heart disease (CHD), as assessed by cardiopulmonary exercise testing (CPET). METHODS: A retrospective analysis was performed of adult patients with CHD who had undergone CPET in a single tertiary center. Diagnoses were divided into repaired tetralogy of Fallot, transposition of the great arteries (TGA) after Senning or...


Impact of Cardiac Resynchronization Therapy on Inflammatory Biomarkers and Card...

Almeida-Morais, L; Abreu, A; Oliveira, MM; Silva Cunha, P; Rodrigues, I; Portugal, G; Rio, P; Soares, RM; Mota Carmo, M; Cruz Ferreira, R

INTRODUCTION: Response to cardiac resynchronization therapy (CRT) can currently be assessed by clinical or echocardiographic criteria, and there is no strong evidence supporting the use of one rather than the other. Reductions in B-type natriuretic peptide (BNP) and C-reactive protein (CRP) have been shown to be associated with CRT response. This study aims to assess variation in BNP and CRP six months after CR...


Optimizing Risk Stratification in Heart Failure and the Selection of Candidates...

Pereira-da-Silva, T; Soares, RM; Papoila, AL; Pinto, I; Feliciano, J; Almeida-Morais, L; Abreu, A; Cruz Ferreira, R

INTRODUCTION AND AIMS: Selecting patients for heart transplantation is challenging. We aimed to identify the most important risk predictors in heart failure and an approach to optimize the selection of candidates for heart transplantation. METHODS: Ambulatory patients followed in our center with symptomatic heart failure and left ventricular ejection fraction ≤40% prospectively underwent a comprehensive baselin...


Reabilitação Cardíaca Após Síndrome Coronária Aguda. Deveremos Continuar a Reab...

Rosa, S; Abreu, A; Filipe, C; Soares, RM; Rio, P; Silva, S; Alves, S; Alves, T; Ferreira, V; Soares, C; Rodrigues, I; Viveiros Monteiro, A; Portugal, G

Introdução: A Reabilitação cardíaca (Rc) é um elemento fundamental na prevenção secundária após síndrome coronária aguda (ScA). A American Association of Cardiovascular and Pulmonary Rehabilitation (AAcPR)definiu critérios de estratificação de risco para os doentes elegíveis para programas de Rc. Contudo, tem sido questionada a integração de doentes de baixo risco em programas estruturados de treino de exercíci...


O Volume da Aurícula Esquerda como Marcador Ecocardiográfico de Prognóstico em ...

Ferreira, F; Galrinho, A; Soares, RM; Branco, LM; Abreu, J; Feliciano, J; Papoila, AL; Virella, D; Leal, A; Cruz Ferreira, R

Introdução: O aumento da aurícula esquerda (AE) é um marcador de mortalidade na população geral. Os doentes com miocardiopatia dilatada (MCD) têm um amplo espetro de tamanhos deAE, mas a importância clínica desta observação tem sido pouco estudada. Objectivo: Avaliar a importância prognóstica a longo prazo do volume da AE (VAE) em doentes com MCD. Métodos: Estudo prospetivo de doentes admitidos durante o ano de...


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