3 documents found, page 1 of 1
Impact of umbilical cord mesenchymal stromal/stem cell secretome and cord blood...
Sousa, André ; Coelho, Pedro; Leite, Fernanda ; Teixeira, Catarina ; Rocha, Ana Catarina ; Santos, Inês ; Baylina, Pilar; Fernandes, RubenProstate cancer (PCa) is the second most common malignancy in men, and the ffth leading cause of death worldwide. Mesenchymal stromal/stem cells (MSC) have been identifed in PCa, although contradictory efects in malignant transformation and tumor progression have been described. Since umbilical cord (UC) MSC and cord blood serum (CBS) are rich in numerous growth and anti-infammatory factors, UC-MSC secretome an...
Does body mass index infuence surgical options and overall survival in breast c...
Luís, Carla ; Fernandes, Rute ; Dias, João ; Pereira, Deolinda ; Machado, Firmino ; Baylina, Pilar; Fernandes, Rúben ; Soares, RaquelObesity is a relevant risk factor in breast cancer (BC), but little is known about the efects of overweight and obesity in surgical outcomes of BC patients. The aim of this study is to analyse surgical options and associated overall survival (OS) in overweight and obese women with BC. In this study, 2143 women diagnosed between 2012 and 2016 at the Portuguese Oncology Institute of Porto (IPO-Porto) were include...
Human umbilical cord mesenchymal stem cells in type 2 diabetes mellitus: the em...
Gomes, Andreia ; Coelho, Pedro; Soares, Raquel ; Costa, RaquelThe umbilical cord has been proved to be an easy-access, reliable, and useful source of mesenchymal stem cells (MSC) for clinical applications due to its primitive, immunomodulatory, non-immunogenic, secretory and paracrine, migratory, proliferative, and multipotent properties. This set of characteristics has recently attracted great research interest in the fields of nanotechnology and regenerative medicine an...