2 documents found, page 1 of 1
Leishmania infantum-derived lipophosphoglycan as an antigen in the accurate ser...
Portela, Ricardo Wagner Dias; Soares, Rodrigo Pedro Pinto; Porfírio Passos, Gabriela; Larangeira, Daniela Farias; Barral, Thiago Assis DoriaLipophosphoglycan (LPG) is the major surface glycoconjugate of Leishmania protozoan and has an important biological role in host-parasite interactions both in the midgut epithelium of the sand fly vector and in the vertebrate macrophages. Canine leishmaniasis (CanL) is a chronic infectious disease predominantly caused by Leishmania infantum. An early and accurate immunodiagnosis of the disease is crucial for ve...
American tegumentary leishmaniasis : effectiveness of an immunohistochemical pr...
Alves, Cibele Fontes; Alves, Cíntia Fontes; Figueiredo, Maria Marta; Souza, Carolina Carvalho de; Coelho, George Luiz Lins Machado; Melo, Maria NormaBackground: American tegumentary leishmaniasis (ATL) is endemic in Latin America, where Brazil has over 27 thousand cases per year. The aim of the present study was to develop an immunohistochemical method (IHC) for ATL diagnosis. For this purpose, we used serum from a dog naturally infected with Leishmania (L) infantum (canine hyperimmune serum) as the primary antibody, followed by a detection system with a se...