20 documents found, page 1 of 2
Harvesting the power of green synthesis: gold nanoparticles tailored for prosta...
Oliveira, Marco; Sousa, André; Sá, Sara; Soares, Sílvia; Pereira, Ana Cláudia; Rocha, Ana Catarina; Pais, Patrick; Ferreira, Diogo; Almeida, CátiaBiosynthetic gold nanoparticles (bAuNPs) present a promising avenue for enhancing biocompatibility and offering an economically and environmentally responsible alternative to traditional production methods, achieved through a reduction in the use of hazardous chemicals. While the potential of bAuNPs as anticancer agents has been explored, there is a limited body of research focusing on the crucial physicochemic...
Determinação de alergénios de amendoim e amêndoa em alimentos comercializados n...
Soares, Renata; Sousa, Carolina; Soares, Sílvia; Moreira, Andreia; Vieira da Silva, Manuela; Freitas, MarisaA sustentabilidade ambiental é um tema de destaque a nível mundial. Considerando os princípios da hierarquia da gestão de resíduos e a maior sensibilização da população para evitar o uso de embalagens descartáveis, é inegável o ressurgimento e expansão das lojas de venda de alimentos a granel (Beitzen-Heineke et al., 2017).
Radiotherapy metastatic prostate cancer cell lines treated with gold nanorods m...
Soares, Sílvia; Aires, Fátima; Monteiro, Armanda; Pinto, Gabriela; Faria, Isabel; Sales, Goreti; Correa-Duarte, Miguel A.; Guerreiro, SusanaMicroRNA (miRNA) modulation has been identified as a promising strategy for improving the response of human prostate cancer (PCa) to radiotherapy (RT). Studies have shown that mimics or inhibitors of miRNAs could modulate the sensitivity of PCa cells to RT. In addition, pegylated gold nanoparticles have been studied as a therapeutic approach to treat PCa cells and/or vehicles for carrying miRNAs to the inside o...
Metabolic Disruption of Gold Nanospheres, Nanostars and Nanorods in Human Metas...
Soares, Sílvia; Pereira, Cláudia; Sousa, André P; Oliveira, Ana Catarina; Sales, M. Goreti F.; Correa-Duarte, Miguel A; Guerreiro, Susana GNanomaterials offer a broad spectrum of applications in biomedicine. The shapes of gold nanoparticles could modulate tumor cell behavior. Spherical (AuNPsp), stars (AuNPst) and rods (AuNPr) shapes of polyethylene glycol coated-gold nanoparticles (AuNPs-PEG) were synthesized. Metabolic activity, cellular proliferation, and reactive oxygen species (ROS) were measured and the impact of AuNPs-PEG in metabolic enzym...
Application of Gold Nanoparticles as Radiosensitizer for Metastatic Prostate Ca...
Soares, Sílvia; Faria, Isabel; Aires, Fátima; Monteiro, Armanda; Pinto, Gabriela; Sales, M. Goreti F.; Correa-Duarte, Miguel A.; Guerreiro, Susana G.More than 50% of all prostate cancer (PCa) patients are treated by radiotherapy (RT). Radioresistance and cancer recurrence are two consequences of the therapy and are related to dose heterogeneity and non-selectivity between normal and tumoral cells. Gold nanoparticles (AuNPs) could be used as potential radiosensitizers to overcome these therapeutic limitations of RT. This study assessed the biological interac...
Fostering customer loyalty in kitesurfing: the case of a Nautical Sports Centre...
Soares, Sílvia; Carvalho, Pedro; Mourão, Maria FilipaIn this study, the relationship between service quality, customer satisfaction, and behavioural intention is investigated within a specialised nautical sports centre that offers kitesurfing in Portugal. Using a path analysis model, this study aims to evaluate the effect of the dimensions of service quality on satisfaction and behavioural intention, as well as the effect of satisfaction on the customer’s behavio...
The magic cocktail: Ampicillin and Biosynthesized gold nanoparticles synergism ...
Oliveira, Marco; Soares, Sílvia; Sá, Sara; Gestoso, Álvaro; Correa-Duarte, Miguel; Baylina, Pilar; Fernandes, Rúben; Pereira, Carla F.Gold nanoparticles (AuNPs) have garnered attention as a potential alternative to conventional antibiotics due to their innovative antibacterial properties. This study demonstrates the successful production of biosynthetic gold nanoparticles (bAuNPs) using Pseudomonas aeruginosa (P. aeruginosa) as spherical nanostructures at 58 ◦C for 24 h, under alkaline pH (9.0). The successful synthesis of bAuNPs was confirme...
Application of gold nanoparticles as radiosensitizer for metastatic prostate ca...
Soares, Sílvia; Faria, Isabel; Aires, Fátima; Monteiro, Armanda; Pinto, Gabriela; Sales, Maria Goreti; Correa-Duarte, Miguel A.; Guerreiro, Susana G.More than 50% of all prostate cancer (PCa) patients are treated by radiotherapy (RT). Radioresistance and cancer recurrence are two consequences of the therapy and are related to dose heterogeneity and non-selectivity between normal and tumoral cells. Gold nanoparticles (AuNPs) could be used as potential radiosensitizers to overcome these therapeutic limitations of RT. This study assessed the biological interac...
Application of gold nanoparticles as radiosensitizer for metastatic prostate ca...
Soares, Sílvia; Faria, Isabel; Aires, Fátima; Monteiro, Armanda; Pinto, Gabriela; Sales, Maria Goreti; Correa-Duarte, Miguel A.; Guerreiro, Susana G.More than 50% of all prostate cancer (PCa) patients are treated by radiotherapy (RT). Radioresistance and cancer recurrence are two consequences of the therapy and are related to dose heterogeneity and non-selectivity between normal and tumoral cells. Gold nanoparticles (AuNPs) could be used as potential radiosensitizers to overcome these therapeutic limitations of RT. This study assessed the biological interac...
Metabolic disruption of gold nanospheres, nanostars and nanorods in human metas...
Soares, Sílvia; Pereira, Cláudia; Sousa, André P.; Oliveira, Ana Catarina; Sales, Maria Goreti; Correa-Duarte, Miguel A.; Guerreiro, Susana G.Nanomaterials offer a broad spectrum of applications in biomedicine. The shapes of gold nanoparticles could modulate tumor cell behavior. Spherical (AuNPsp), stars (AuNPst) and rods (AuNPr) shapes of polyethylene glycol coated-gold nanoparticles (AuNPs-PEG) were synthesized. Metabolic activity, cellular proliferation, and reactive oxygen species (ROS) were measured and the impact of AuNPs-PEG in metabolic enzym...