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Tofacitinib: An Option for Acute Severe Ulcerative Colitis?

Santos,Sara; Gamelas,Verónica; Saraiva,Rita; Simões,Guilherme; Saiote,Joana; Ramos,Jaime

Abstract Tofacitinib has emerged as a new option for ulcerative colitis. Its rapid absorption, metabolism, and clinical improvement make it an interesting option for rescue therapy in acute severe ulcerative colitis (ASUC), a situation with limited therapeutic options in patients with a long-term disease course and multiple drug failure. The management of ASUC in this setting becomes challenging, underlying the...

Date: 2022   |   Origin: SciELO Portugal

Whipple’s Disease with Colonic Involvement: A Rare Endoscopic Documentation

Gamelas,Verónica; Canha,Ines; Pimentel,João; Santos,Sara; Borges,Verónica; Bernardes,Carlos

Date: 2022   |   Origin: SciELO Portugal

Cytomegalovirus Colitis Mimicking Rectal Tumour in an Undiagnosed HIV Patient

Rocha,Manuel; Borges,Verónica; Simões,Guilherme; Santos,Sara; Gamelas,Verónica; Bernardes,Carlos

Introduction: Cytomegalovirus (CMV) is the most common opportunistic agent in HIV-infected patients. It can affect the entire gastrointestinal tract, but frequently involves the oesophagus and the colon. Case Report: We report the case of a 70-year-old female, ultimately diagnosed with HIV infection, whose inaugural clinical manifestation was CMV colitis with endoscopic findings resembling a rectal tumour in wh...

Date: 2020   |   Origin: SciELO Portugal

Prescription Pattern of Proton Pump Inhibitors at Hospital Admission and Discharge

Gamelas,Verónica; Salvado,Vera; Dias,Luís

Background: Proton pump inhibitors (PPI) have reportedly been used in inappropriate clinical settings, often leading to an increased risk of adverse effects, drug interactions, and costs. Aim: The aim of this study was to evaluate the adequacy of PPI prescription in an internal medicine ward. Methods: The discharged home inpatients of a segment in the medicine department of a central hospital in the first trime...

Date: 2019   |   Origin: SciELO Portugal

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