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Alterations of bovine nucleus pulposus cells with aging
Molinos, Maria; Fiordalisi, Morena F.; Caldeira, Joana; Almeida, Catarina R.; Barbosa, Mário A.; Gonçalves, Raquel M.Aging is one of the major etiological factors driving intervertebral disc (IVD) degeneration, the main cause of low back pain. The nucleus pulposus (NP) includes a heterogeneous cell population, which is still poorly characterized. Here, we aimed to uncover main alterations in NP cells with aging. For that, bovine coccygeal discs from young (12 months) and old (10-16 years old) animals were dissected and primar...
Data: 2023
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Origem: RIA - Repositório Institucional da Universidade de Aveiro