4 documents found, page 1 of 1
Multiple sclerosis, disease-modifying therapies and COVID-19: A systematic revi...
Cabreira, V; Abreu, P; Soares-Dos-Reis, R; Guimarães, J; Sá, MJUnderstanding the risks of COVID-19 in patients with Multiple Sclerosis (MS) receiving disease-modifying therapies (DMTs) and their immune reactions is vital to analyze vaccine response dynamics. A systematic review on COVID-19 course and outcomes in patients receiving different DMTs was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Emerging data on SAR...
Intensive Blood Pressure Treatment Reduced Stroke Risk in Patients With Albumin...
Leitão, L; Soares-Dos-Reis, R; Neves, JS; Baptista, RB; Bigotte Vieira, M; Mc Causland, FRBackground and Purpose- Albuminuria is associated with stroke risk among individuals with diabetes. However, the association of albuminuria with incident stroke among nondiabetic patients is less clear. Methods- We performed a post hoc analysis of the SPRINT (Systolic Blood Pressure Intervention Trial), which examined the effect of higher versus lower intensity blood pressure management on mortality in 8913 par...
Ocular neuromyotonia
Soares-Dos-Reis, R; Martins, AI; Brás, A; Matos, A; Bento, C; Lemos, JOcular neuromyotonia is a rare, albeit treatable, ocular motor disorder, characterised by recurrent brief episodes of diplopia due to tonic extraocular muscle contraction. Ephaptic transmission in a chronically damaged ocular motor nerve is the possible underlying mechanism. It usually improves with carbamazepine. A 53-year-old woman presented with a 4-month history of recurrent episodes of binocular vertical d...
Emerging biosensing technologies for neuroinflammatory and neurodegenerative di...
Abreu, C; Soares-Dos-Reis, R; Melo, PN; Relvas, JB; Guimarães, J; Sá, M; Cruz, AP; Pinto, INeuroinflammation plays a critical role in the onset and progression of many neurological disorders, including Multiple Sclerosis, Alzheimer’s and Parkinson’s diseases. In these clinical conditions the underlying neuroinflammatory processes are significantly heterogeneous. Nevertheless, a common link is the chronic activation of innate immune responses and imbalanced secretion of pro and anti-inflammatory media...