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Global gene expression analysis of Streptococcus agalactiae at exponential grow...

Silvestre, Inês; Borges, Vítor; Duarte, Sílvia; Nunes, Alexandra; Sobral, Rita; Vieira, Luís; Gomes, João Paulo; Borrego, Maria José

A comparative overview of the global gene expression levels of S. agalactiae reference strain NEM316 at the exponential growth phase was done through RNA-sequencing. The expression levels of 47 genes potentially linked to virulence evidenced that: i) the major nuclease, GBS_RS03720/gbs0661, presented higher mean expression values than the remainder of DNase genes; ii) the genetic pilus island PI-2a genes presen...


Identification and Antibiotic-Susceptibility Profiling of Infectious Bacterial ...

Maugeri, Gaetano; Lychko, Iana; Sobral, Rita; Roque, Ana C. A.

This work was supported by the European Research Council through the grant reference SCENT-ERC-2014-STG-639123 (2015-2020), and by the Unidade de Ciencias Biomoleculares Aplicadas-UCIBIO, which is financed by national funds from FCT/MEC (UID/Multi/04378/2013) and co-financed by the ERDF under the PT2020 Partnership Agreement (POCI-01-0145-FEDER-007728).; Antimicrobial resistance is one of the most worrying thre...


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