Acute leptospirosis has a large part of its clinical manifestations as a function of the vascular injury with endothelial cell damage provided by the infection. Fever, jaundice, renal failure, nephritis, hemolytic anemia, hemoglobinuria, and fatal pulmonary haemorrhage are relevant clinical features. The lesion is probably due to deposits of immune complexes in the small vessels of the affected organs. The acti...
Anemia in Leptospira interrogans infected individuals is one of the most common complications found in the severe form of the disease. Iron plays an important role in the hematopoietic processes; however, its precise metabolism on individuals with leptospirosis is still unknown. Therefore, the aim of this study was to analyze the classic iron markers associated to the storage process in hamsters experimentally ...