2 documents found, page 1 of 1
Screening for bipolar spectrum disorders : a comprehensive meta-analysis of acc...
Carvalho, André F.; Takwoingi, Yemisi; Sales, Paulo Marcelo G.; Soczynska, Joanna K.; Köhler, Cristiano A.; Freitas, Thiago H.; Quevedo, JoãoBackground: Bipolar spectrum disorders are frequently under-recognized and/or misdiagnosed in various settings. Several in fl uential publications recommend the routine screening of bipolar disorder. A systematic review and meta-analysis of accuracy studies for the bipolar spectrum diagnostic scale (BSDS), the hypomania checklist (HCL-32) and the mood disorder questionnaire (MDQ) were performed. Methods: The Pu...
Prevention and reversal of ketamine-induced schizophrenia related behavior by m...
Monte, Aline Santos; Souza, Greicy Coelho de; McIntyre, Roger S.; Soczynska, Joanna K.; Santos, Júnia Vieira dos; Cordeiro, Rafaela CarneiroIt has been hypothesized that oxidative imbalance and alterations in nitrergic signaling play a role in the neurobiology of schizophrenia. Preliminary evidence suggests that adjunctive minocycline treatment is efficacious for cognitive and negative symptoms of schizophrenia. This study investigated the effects of minocycline in the prevention and reversal of ketamine-induced schizophrenia-like behaviors in mice...