35 documents found, page 1 of 4
Plasma levels of ursodeoxycholic acid in black bears, Ursus americanus
Sola, S; Garshelis, DL; Amaral, JD; Noyce, KV; Coy, PL; Steer, CJ; Iaizzo, PA; Rodrigues, CMPTo date, no other studies have examined the seasonal changes in circulating levels of various bile acids in the plasma of wild North American black bears, Ursus americanus. Using gas chromatography, bile acid concentrations were measured in plasma samples
Nuclear steroid receptors modulate cellular trafficking of ursodeoxycholic acid...
Sola, S; Amaral, JD; Castro, RE; Ramalho, RM; Kren, BT; Steer, CJ; Rodrigues, CMP
Nuclear translocation of UDCA by the glucocorticoid receptor is required to red...
Sola, S; Amaral, J; Castro, RE; Ramalho, RM; Borralho, PM; Kren, BT; Tanaka, H; Steer, CJ; Rodrigues, CMPUrsodeoxycholic acid (UDCA) inhibits classical mitochondrial pathways of apoptosis by either directly stabiliz* mitochondrial membranes or modulating specific upstream targets. Furthermore, UDCA regulates apoptosis-related genes from transforming growth f
Modulation of neurotoxicity associated with Alzheimer's disease-linked amyloid ...
Ramalho, RM; Borralho, PM; Sola, S; Castro, RE; Amaral, JD; Rodrigues, CMP
Increased apoptosis and decreased p53 and Bax expression in colorectal tumours
Borralho, PM; Ravasco, P; da Silva, IBM; Castro, RE; Ramalho, RM; Sola, S; Correia, L; Fernandes, A; Camilo, ME; Rodrigues, CMP
A distinct microarray gene expression profile in primary rat hepatocytes incuba...
Castro, RE; Sola, S; Ma, XM; Ramalho, RM; Kren, BT; Steer, CJ; Rodrigues, CMPBackground/Aims: Ursodeoxycholic acid (UDCA) and its taurine-conjugated derivative, TUDCA, modulate cell death and cell cycle regulators, such as E2F-1 and p53. However, precise pathways underlying UDCA's effects are not fully understood. The aim of this
Nuclear translocation of UDCA via the glucocorticoid receptor is essential for ...
Sola, S; Amaral, JD; Castro, RE; Ramalho, RM; Borralho, PM; Kren, BT; Steer, C; Rodrigues, CM
Distinct gene expression profile associated with ursodeoxycholic acid treatment...
Castro, RE; Sola, S; Ramalho, RM; Kren, BT; Steer, CJ; Rodrigues, CM
Steroid nuclear receptors modulate the anti-apoptotic effects of ursodeoxycholi...
Sola, S; Castro, RE; Kren, BT; Steer, CJ; Rodrigues, CMP
Enhanced apoptosis and Bcl-2 protein production in the liver of patients with s...
Ramalho, RM; Cortez-Pinto, H; Sola, S; Castro, RE; Camilo, ME; Moura, MC; Rodrigues, CMP