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Butylone enantioseparation and ecotoxicity evaluation on Daphnia magna

Carvalho, A. R.; Morão, A. M.; Gonçalves, V. M. F.; Tiritan, M. E.; Lado, A. R.; Carrola, J. S.; Amorim, M. M.; Ribeiro, C.

Background: The synthetic drug butylone (2-methylamino-1-(3,4-methylenedioxyphenyl)butan-1-one, BTL) is a chiral cathinone consumed in the form of racemate [1]. After consumption, BTL is metabolized and excreted along with its metabolites, and its residues are carried by sewerage systems to wastewater treatment plants (WWTPs) [2]. Both human metabolism and biodegradation in WWTPs may be enantioselective causing...

Date: 2023   |   Origin: Scientific Letters

MDA effects on morphophysiology and reproduction of Daphnia magna – preliminary...

Morão, A. M.; Carvalho, A. R.; Couto, C.; Carrola, J. S.; Costa, P.; Castro, B.; Tiritan, M. E.; Ribeiro, C.

Background: Psychoactive substances and their metabolites are considered emergent contaminants, raising environmental concerns due to the continuous input into aquatic ecosystems [1]. MDA (3,4-methylenedioxyamphetamine) is a pharmacologically active substance that represents the major metabolite of 3,4-methylenedioxymethamphetamine (MDMA); MDA may be present in MDMA preparations or occur as an illegal psychoact...

Date: 2023   |   Origin: Scientific Letters

Sustainable and active ageing: development and application of SAVING methodology

Almeida-Silva, Marina; Manteigas, Vítor; Teixeira, A. M.; Carvalho, A. R.; Moreira, J.; Tavares, David; Tomás, Maria Teresa; Monteiro, Ana

The SAVING project intends to develop research activities applying the best strategies and good practices regarding the promotion of an active, healthy and sustainable aging in relation to social, economic, environmental and pedagogic aspects. This project aims to create a Sustainable and Active Ageing Program named SAVING Program to promote the transition to sustainable aging in Elderly Care Centres (ECCs). SA...


Selective enrichment of hydrocarbonoclastic bacteria producing storage compound...

Carvalho, A. R.; Castro, Paulo; Rocha, I.; Alves, M. M.; Pereira, M. A.

Hydrocarbonoclastic bacteria are important players in bioremediation of hydrocarbon contaminated ecosystems with additional potential for application in biological treatment of industrial wastewaters. Synthesis and accumulation of storage lipids such as triacylglycerols (TAGs) and wax esters (WEs), as well as polyhydroxyalkanoate (PHA) polymers, has been reported in this group of bacteria when submitted to grow...


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