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Lipophilic marine toxins in sediments from Arrábida marine protected area, Port...

Soliño, Lucia; Braga, Ana Catarina; Lobo-Arteaga, Jorge; Reis Costa, Pedro

During the development and senescence of harmful algal blooms (HAB), most of the algae cells not ingested by grazers or filter-feeding organisms sink to the bottom, making sediments important reservoirs of algae toxins. In this study, lipophilic marine toxins were determined in the sediments collected from depths ranging from 5 to 145 m depth in the marine protected area of Arrabida (southwest Portuguese coast)...


Lipophilic marine toxins in sediments from Arrábida marine protected area, Port...

Soliño, Lucia; Braga, Ana Catarina; Lobo-Arteaga, Jorge; Reis Costa, Pedro

During the development and senescence of harmful algal blooms (HAB), most of the algae cells not ingested by grazers or filter-feeding organisms sink to the bottom, making sediments important reservoirs of algae toxins. In this study, lipophilic marine toxins were determined in the sediments collected from depths ranging from 5 to 145 m depth in the marine protected area of Arrabida ´ (southwest Portuguese coas...


No β-N-Methylamino-L-alanine (BMAA) was detected in stranded cetaceans from Gal...

Soliño, Lucia; Kim, Sea-Yong; López, Alfredo; Covelo, Pablo; Rydberg, Sara; Reis Costa, Pedro; Lage, Sandra

The neurotoxin β-N-methylamino-L-alanine (BMAA), a non-proteinogenic amino acid produced by several species of both prokaryotic (cyanobacteria) and eukaryotic (diatoms) microorganisms, has been proposed to be associated with the development of neurodegenerative diseases. At first, BMAA appeared to be ubiquitously present worldwide in various organisms, from aquatic and terrestrial food webs. However, recent stu...


Cytotoxic and hemolytic activities of extracts of the fish parasite dinoflagell...

Moreira, Márcio; Soliño, Lucia; Marques, Cátia L.; Laizé, Vincent; Pousão-Ferreira, Pedro; Fidalgo E Costa, Pedro; Soares, Florbela

The dinoflagellate Amyloodinium ocellatum is the etiological agent of a parasitic disease named amyloodiniosis. Mortalities of diseased fish are usually attributed to anoxia, osmoregulatory impairment, or opportunistic bacterial infections. Nevertheless, the phylogenetic proximity of A. ocellatum to a group of toxin-producing dinoflagellates from Pfiesteria, Parvodinium and Paulsenella genera suggests that it m...


Distribution, identification and cytotoxicity of Gambierdiscus (Dinophyceae) in...

Godinho, Lia; Soliño, Lucia; Churro, Catarina; Timoteo, Viriato; Santos, Carolina; Gouveia, Neide; Diogène, Jorge; Reis Costa, Pedro

The emerging threat of ciguatera poisoning (CP) in Europe has been associated with fish captured in the Canary Islands (Spain) and Selvagens Islands (Portugal). The first are heavily populated islands where numerous scientific studies have been carried out. Conversely, the Selvagens Islands are a nature reserve with low human pressure that have been rarely surveyed in terms of the marine benthic microalgae, inc...


New insights into the occurrence of paralytic shellfish toxins in the oceanic p...

Soliño, Lucia; Gouveia, Neide; Timóteo, Viriato; Reis Costa, Pedro

Pufferfish are some of the most poisonous marine organisms due to their capability to accumulate potent neurotoxins such as tetrodotoxins (TTXs) and paralytic shellfish toxins (PSTs). Several species are consumed, mainly in Asiatic countries, for the quality of their flesh, which may cause severe human poisoning every year due to errors in preparation. Lagocephalus lagocephalus the oceanic pufferfish, is a cosm...


High Levels of Tetrodotoxin (TTX) in Trumpet Shell Charonia lampas from the Por...

Reis Costa, Pedro; Giráldez, Jorge; Rodrigues, Susana Margarida; Leão, José Manuel; Pinto, Estefanía; Soliño, Lucia; Gago-Martínez, Ana

Tetrodotoxin (TTX) is a potent neurotoxin, considered an emerging toxin in Europe where recently a safety limit of 44 µg TTX kg-1 was recommended by authorities. In this study, three specimens of the large gastropod trumpet shell Charonia lampas bought in a market in south Portugal were analyzed using a neuroblastoma cell (N2a) based assay and by LC-MS/MS. N2a toxicity was observed in the viscera of two individ...


An update on ciguatoxins and CTX-like toxicity in fish from different trophic l...

Reis Costa, Pedro; Estévez, Pablo; Soliño, Lucia; Castro, David; Rodrigues, Susana Margarida; Timoteo, Viriato; Leao-Martins, José Manuel

The Selvagens Islands, which are a marine protected area located at the southernmost point of the Portuguese maritime zone, have been associated with fish harboring ciguatoxins (CTX) and linked to ciguatera fish poisonings. This study reports the results of a field sampling campaign carried out in September 2018 in these remote and rarely surveyed islands. Fifty-six fish specimens from different trophic levels ...


Effects of the marine biotoxins Okadaic acid and Dinophysistoxins on fish

Corriere, Mauro; Soliño, Lucia; Reis Costa, Pedro

Natural high proliferations of toxin-producing microorganisms in marine and freshwater environments result in dreadful consequences at the socioeconomically and environmental level due to water and seafood contamination. Monitoring programs and scientific evidence point to harmful algal blooms (HABs) increasing in frequency and intensity as a result of global climate alterations. Among marine toxins, the okadai...


Global impact of ciguatoxins and ciguatera fish poisoning on fish, fisheries an...

Soliño, Lucia; Reis Costa, Pedro

Ciguatera fish poisoning (CFP) is one of the most devastating food-borne illnesses caused by fish consumption. Ciguatoxins (CTXs) are potent neurotoxins synthesized by the benthic microalgae Gambierdiscus spp. and Fukuyoa spp. that are transmitted to fish by grazing and predation. Despite the high incidence of CFP, affecting an estimated number of 50,000 persons per year in tropical and subtropical latitudes, t...


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