Metagenomic next-generation sequencing (mNGS), the shotgun sequencing of RNA and DNA from clinical samples, has proved useful for broad-spectrum pathogen detection and the genomic surveillance of viral outbreaks. An additional target enrichment step is generally needed for high-sensitivity pathogen identification in low-titre infections, yet available methods using PCR or capture probes can be limited by high c...
University of California San Francisco. San Francisco, California, USA.; University of Oxford. Oxford, UK.; Federal University of Bahia. Salvador, BA, Brasil.; University of California San Francisco. San Francisco, California, USA.; University of Washington. Seattle, Washington, USA.; Hospital Alian?a. Salvador, BA, Brasil.; Federal University of Bahia. Salvador, BA, Brasil.; Funda??o Gon?alo Moniz. Centro de P...