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S100B inhibition protects from chronic experimental autoimmune encephalomyelitis

Barros, Catarina; Barateiro, Andreia; Neto, Alexandre; Soromenho, Beatriz; Basto, Afonso; Mateus, Joana; Xapelli, Sara; Sebastião, Ana M; Brites, Dora

Studies have correlated excessive S100B, a small inflammatory molecule, with demyelination and associated inflammatory processes occurring in multiple sclerosis. The relevance of S100B in multiple sclerosis pathology brought an emerging curiosity highlighting its use as a potential therapeutic target to reduce damage during the multiple sclerosis course, namely during inflammatory relapses. We examined the rele...

Date: 2022 | Origin: Repositório da Universidade de Lisboa

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