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Toward a Consensus on Centralization in Surgery

Vonlanthen, R; Lodge, P; Barkun, J; Farges, O; Rogiers, X; Soreide, K; Kehlet, H; Reynolds, J; Käser, S; Naredi, P; Borel-Rinkes, I; Biondo, S

Objectives: To critically assess centralization policies for highly specialized surgeries in Europe and North America and propose recommendations. Background/methods: Most countries are increasingly forced to maintain quality medicine at a reasonable cost. An all-inclusive perspective, including health care providers, payers, society as a whole and patients, has ubiquitously failed, arguably for different reaso...


Recurrence After Operative Management of Intrahepatic Cholangiocarcinoma

Hyder, O; Hatzaras, I; Sotiropoulos, G; Paul, A; Alexandrescu, S; Marques, H; Pulitano, C; Barroso, E; Clary, B; Aldrighetti, L; Ferrone, C; Zhu, A

INTRODUCTION: Data on recurrence after operation for intrahepatic cholangiocarcinoma (ICC) are limited. We sought to investigate rates and patterns of recurrence in patients after operative intervention for ICC. METHODS: We identified 301 patients who underwent operation for ICC between 1990 and 2011 from an international, multi-institutional database. Clinicopathologic data, recurrence patterns, and recurrence...


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