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Unveiling the Toxicity of Fine and Nano-Sized Airborne Particles Generated from...
Bessa, Maria João; Brandão, Fátima; Fokkens, Paul H.B.; Leseman, Daan L.A.C.; Boere, A. John F.; Cassee, Flemming R.; Salmatonidis, ApostolosHigh-energy industrial processes have been associated with particle release into workplace air that can adversely affect workers’ health. The present study assessed the toxicity of incidental fine (PGFP) and nanoparticles (PGNP) emitted from atmospheric plasma (APS) and high-velocity oxy-fuel (HVOF) thermal spraying. Lactate dehydrogenase (LDH) release, 2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene disulfonate...
In Vitro Toxicity of Industrially Relevant Engineered Nanoparticles in Human Al...
Bessa, Maria João; Brandão, Fátima; Fokkens, Paul H.B.; Leseman, Daan L.A.C.; Boere, A. John F.; Cassee, Flemming R.; Salmatonidis, ApostolosDiverse industries have already incorporated within their production processes engineered nanoparticles (ENP), increasing the potential risk of worker inhalation exposure. In vitro models have been widely used to investigate ENP toxicity. Air-liquid interface (ALI) cell cultures have been emerging as a valuable alternative to submerged cultures as they are more representative of the inhalation exposure to airbo...