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Avaliação da construtibilidade de pastas de gesso para impressão 3D

Gaspar, Luís; Pedrosa, Ana Rita; Peixinho, Ana; Gouveia, Liliana; Sousa, Ângela; Freire, Maria Teresa; Gaspar, Florindo

A manufatura aditiva, também conhecida como impressão 3D, tem revolucionado os processos de fabrico em diversas áreas, da construção civil à medicina. Esta tecnologia possibilita a produção de peças com formas complexas, reduzindo a mão de obra, tempo de execução e desperdício de matéria-prima. Na construção civil, tem sido estudado o uso de argamassas de cimento aplicadas por extrusão, existindo já alguns edif...


Advances in structure-based drug design targeting membrane protein markers in p...

Batista-Silva, João P.; Gomes, Diana; Sousa, Sérgio F.; Sousa, Ângela; Passarinha, Luís A.

© 2024 The Author(s). Published by Elsevier Ltd.; Prostate cancer (PCa) is one of the leading cancers in men and the lack of suitable biomarkers or their modulators results in poor prognosis. Membrane proteins (MPs) have a crucial role in the development and progression of PCa and can be attractive therapeutic targets. However, experimental limitations in targeting MPs hinder effective biomarker and inhibitor d...


Specific Six-Transmembrane Epithelial Antigen of the Prostate 1 Capture with Ge...

Batista-Silva, João; Gomes, Diana; Barroca-Ferreira, Jorge; Gallardo, Eugénia; Sousa, Ângela; Passarinha, Luís A.

Funding Information: The authors acknowledge the support from FEDER funds through the POCI-COMPETE 2020–Operational Programme Competitiveness and Internationalisation in Axis I–Strengthening Research, Technological Development and Innovation (Project POCI-01-0145-FEDER-007491).This work was also supported by the Associate Laboratory Institute for Health and Bioeconomy–i4HB (project LA/P/0140/2020) which are fin...


Development and Characterization of Quercetin-Loaded Delivery Systems for Incre...

Ferreira, Miguel; Gomes, Diana; Neto, Miguel; Passarinha, Luís A.; Costa, Diana; Sousa, Ângela

Funding Information: The microscopy facility used in the development of this work is part of the PPBI-Portuguese Platform of BioImaging and is partially supported by the Project POCI-01-0145-FEDER-022122. Publisher Copyright: © 2023 by the authors.; Quercetin is a natural flavonoid with high anticancer activity, especially for related-HPV cancers such as cervical cancer. However, quercetin exhibits a reduced aq...


Volatilomics as an Emerging Strategy to Determine Potential Biomarkers of Femal...

Brinca, Ana Teresa; Anjos, Ofélia; Alves, Maria Manuel Casteleiro; Sousa, Ângela; Oliani, António Hélio; Breitenfeld, Luiza; Passarinha, Luís A.

Funding Information: This work is part of the project Centro-01-0145- FEDER-000019—C4—Centro de Competências em Cloud Computing supported by the European Regional Development Fund through the “Programa Operacional Regional do Centro (Centro 2020)—Sistema de Apoio à Investigação Científica e Tecnológica—Programas Integrados de IC&DT (Covilhã)”. The authors acknowledge the Laboratório de Fármaco-Toxicologia for t...


Development of WRAP5 Peptide Complexes for Targeted Drug/Gene Co-Delivery towar...

Neves, Ana Raquel; Albuquerque, Tânia; Faria, Rúben; Gonçalves, Ana M.; Santos, Cecília; Vivès, Eric; Boisguérin, Prisca; Passarinha, Luís A.

Funding Information: This work was supported by FEDER funds through the POCI-COMPETE 2020—Operational Program Competitiveness and Internationalization in Axis I—strengthening research, technological development, and innovation (Project POCI-01-0145-FEDER-007491). The microscopy facility used in the development of this work is part of the PPBI-Portuguese Platform of BioImaging and is partially supported by the P...


Follicular Fluid

Brinca, Ana Teresa; Ramalhinho, Ana Cristina; Sousa, Ângela; Oliani, António Hélio; Breitenfeld , Luiza; Passarinha, Luís A.; Gallardo, Eugénia

The Associate Laboratory Institute for Health and Bioeconomy–i4HB (project LA/P/0140/2020), which are financed by National Funds from FCT/MCTES. This work was supported by operation Centro-01-0145-FEDER-000019-C4-Centro de Competências em Cloud Computing, cofinanced by the European Regional Development Fund (ERDF) through the Programa Operacional Regional do Centro (Centro 2020), in the scope of the Sistema de ...


Maximization of the Minicircle DNA Vaccine Production Expressing SARS-CoV-2 RBD

Ventura, Cathy; Eusébio, Dalinda; Gonçalves, Ana M.; Barroca-Ferreira, Jorge; Costa, Diana; Cui, Zhengrong; Passarinha, Luís A.; Sousa, Ângela

LA/P/0140/2020 of the Associate Laboratory Institute for Health and Bioeconomy-i4HB. Diana Costa acknowledges research program contract I(SFRH/BD/10201/2020. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.; Nucleic acid vaccines have been proven to be a revolutionary technology to induce an efficient, safe and rapid response against pandemics, like the coronavirus disease (COVID-1...


Taxifolin and Lucidin as Potential E6 Protein Inhibitors

Gomes, Diana; Yaduvanshi, Shivani; Silvestre, Samuel; Duarte, Ana Paula; Santos, Adriana O.; Soares, Christiane P.; Kumar, Veerendra; Passarinha, Luís

This work was supported by the Foundation for Science and Technology (FCT), through funds from the State Budget, and by the European Regional Development Fund through the “Pro-grama Operacional Regional do Centro (Centro 2020)—Sistema de Apoio à Investigação Científica e Tecnológica—Programas Integrados de IC&DT” (Project Centro-01-0145-FEDER-000019—C4—Centro de Competências em Cloud Computing). project LA/P/01...


Advances in Membrane-Bound Catechol-O-Methyltransferase Stability Achieved Usin...

Gonçalves, Ana M.; Sousa, Ângela; Pedro, Augusto Q.; Romão, Maria J.; Queiroz, João A.; Gallardo, Eugénia; Passarinha, Luís A.

Funding: The authors acknowledge the support from FEDER funds through the POCI—COMPETE 2020—Operational Program Competitiveness and Internationalization in Axis I—Strengthening research, technological development, and innovation (Project POCI-01-0145-FEDER-007491) and National Funds (Project UID/Multi/00709/2013) LA/P/0006/2020, financed by national funds through the Portuguese Foundation for Science and Techno...


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