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Endocan as a marker of endotheliitis in COVID-19 patients
Reina-Couto, Marta; Alves, David; Silva-Pereira, Carolina; Pereira-Terra, Patrícia; Martins, Sandra; Bessa, João; Teixeira-Santos, Luísa; Pinho, DoraPublisher Copyright: © 2025. The Author(s).; BACKGROUND AND AIMS: Endocan has been scarcely explored in COVID-19, especially regarding its modulation by veno-venous extracorporeal membrane oxygenation (VV-ECMO), hypertension or previous renin-angiotensin-aldosterone system (RAAS) inhibitors treatment. We compared endocan and other endotheliitis markers in hospitalized COVID-19 patients and assessed their modula...
Diagnóstico e Seguimento Laboratorial de Doentes com Mieloma Múltiplo
Pires, Ana Marta; Barreto, João Pedro; Caetano, Joana; Rego De Sousa, Maria José; Geraldes, Catarina; Fernandes, Bruno; Coucelo, MargaridaMultiple myeloma is a neoplasm of plasma cells that in most cases is associated with the secretion of monoclonal immunoglobulins and can involve multiple organs. Its timely diagnosis is essential to limit or avoid irreversible damage and dysfunction of target organs. Appropriate initial stratification of patients allows for optimization in the selection and sequence of therapy, as well as proper follow-up durin...
Resolvin E1-Chemerin receptor 1 axis is dysregulated in critical COVID-19 patients
Silva-Pereira, Carolina; Reina-Couto, Marta; Pereira-Terra, Patrícia; Teixeira-Santos, Luísa; Martins, Sandra; Pinho, Dora; Soares, Miguel LuzPublisher Copyright: © 2025 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license. http://creativecommons.org/licenses/by/4.0/; Resolvin E1 (RvE1) and Resolvin D1 (RvD1) are key resolvins implicated in inflammation resolution of respiratory and infectious diseases. In contrast to cytokines, they have been scarcely explored in COVID-19 and their ability for discriminating...
Multiple Myeloma Laboratory Diagnostics Made Simple
Pires, Ana Marta; Barreto, João Pedro; Caetano, Joana; Soares, Maria José; Geraldes, Catarina; Fernandes, Bruno; Coucelo, Margarida; Chacim, SérgioPublisher Copyright: © 2025 by the authors.; Multiple myeloma is a clonal plasma cell malignancy with a highly variable range of clinical manifestations. Over recent decades, substantial progress has been made in laboratory diagnostics, which has deepened our understanding of disease biology, improved risk stratification, and informed treatment strategies. In an era of transformation and innovation, conventiona...
Coutinho's method for the altitude
Canas, António Costa; Marabujo, Magda Ramires; Sousa, TeresaUID/MAT/00297/2019; In the first aerial crossing of the South Atlantic, by Gago Coutinho and Sacadura Cabral in 1922, several methods of astronomical maritime navigation were used with adaptions to aerial navigation. In order to apply these methods, the navigator needed to know the approximate altitude of the aircraft so that its position could be determined. The instrument available at that time, the altimeter...