15 documents found, page 1 of 2

Exploring rabbit skin as a novel decellularized dermal substitute for burn woun...

Aim: Burn wounds represent a significant medical challenge. Autografts remain the standard treatment, however, are unsuitable for deep or extensive burns(1). Decellularized skin xenografts offer a viable alternative, having significantly reduced immunogenicity, still there is currently no skin-derived decellularized xenografic matrix due to its low resemblance to human skin (2)(3). This study proposes decellula...

Is decellularized rabbit dermis a viable option for skin wound healing and rege...

Burn wounds remain a significant challenge in medical care, requiring effective wound coverage to restore the skin barrier and promote healing or support skin reconstruction. The use of autologous grafts as substitutes is still the standard treatment, however, it is not suitable for deep and extensive burns (1). Decellularized skin allografts and xenografts have emerged as suitable options, using decellularizat...

Is decellularized rabbit dermis a viable option for skin wound healing and rege...

Burn wounds remain a major clinical challenge, requiring effective coverage to restore the skin barrier and support healing. Autologous grafts are the standard treatment but are limited in deep or extensive burns [1]. Decellularized allografts and xenografts offer alternatives by removing immunogenic material while preserving ECM components [2]. Considering that xenografts source availability is significantly h...

Exploring new biobased material sources as platforms to advance skin wound heal...

Chronic wounds are one of the major therapeutic and healthcare challenges affecting the population globally. One of the research interests of the Biomaterials and Biomedical Technology Lab (BBT Lab) is to explore the potential of biobased material platforms to advance skin wound healing and regeneration solutions. From the use of natural based biopolymers such as silk fibroin (SF) or sulfated exopolysaccharides...

Valorization of rabbit skin for the development of decellularized matrices for ...

Caught in the middle of the transition to a circular economy and emergent call for sustainable solutions, the agro-food industry is undoubtedly a sector that needs action. With a significant generation of by-products, the search for reuse methods to reduce its environmental impact while enhancing its economic value is necessary. The utilization of animal tissue by-products, namely skin, emerges as a promising o...

Os desafios e oportunidades do turismo de saúde e bem-estar. O caso das termas ...

Este estudo analisa as potencialidades da Estância Termal de S. Pedro do Sul, possuidora de uma série de recursos naturais e infraestrutura turística que a tornam atraente para os visitantes. Os objetivos assentam em estudar as motivações dos turistas que procuram as termas como ambiente de férias para que os diferentes players da estância termal consigam responder às novas exigências do mercado

Perception of the image of thermal spas in Portugal

The image of destinations is of great importance in the process of developing tourism for a location, acting not only as a way of differentiating itself from its potential competitors, but, mainly, as an attempt to provide economic support for the sustainable development of the destination (Chagas, 2009). The spa sector in Portugal assumes a growing importance in regions with low population density, where most ...

SKIN2SKIN: decellularized rabbit dermal matrix as a potential bio-substitute of...

Familial aggregation of maxillary lateral incisor agenesis

In spite of recent developments, data regarding the genes responsible for the less severe forms of hypodontia are still scarce and controversial. This study addressed the hypothesis that agenesis of maxillary lateral incisors (MLIA) is a distinct type of hypodontia, by evaluating its familial aggregation and the occurrence of other types of ageneses or microdontia in probands' relatives. Sixty-two probands with...

The C677T polymorphism in MTHFR is not associated with migraine in Portugal

Migraine is a debilitating disorder affecting a large proportion of the population. The effect of methylenetetrahydrofolate reductase (GeneID: 4524) polymorphisms in migraine etiology and development has been a theme of great interest. Several populations were evaluated with contradictory results. In this case-control study, we investigated the effect of the C677T polymorphism in MTHFR, as a genetic risk factor...