178 documents found, page 1 of 18
From dots to dynamics: searching the complexities of prehistoric mobility in th...
Texugo, André; Sánchez de Oro, Pablo; Sousa, Ana CatarinaThis study explores prehistoric mobility networks in the Lisbon Peninsula, focusing on the Chalcolithic and Late Bronze Age periods. Utilising Least Cost Path (LCP) methodologies and Tobler's Hiking Function, movement patterns and connectivity between settlements were analysed. The research reveals a complex landscape of human interactions and environmental adaptations, highlighting social and economic transfor...
Sulfonyldibenzoate coordination polymers as bioactive dopants for polysaccharid...
Fernandes, Tiago A.; Macedo, Filipa; Cabral, Rafaela G.; Guiu, Telma; Franco, Chris H. J.; Jorge, Paula; Sousa, Ana Catarina; André, Vânia; Cerca, NunoThis work describes the preparation, characterization, and antimicrobial properties of bioactive silver(I) and copper(II) coordination polymers (bioCPs) and derived biopolymer materials. Two bioCPs, [Ag2(6-sdba)]n (1) and [Cu(4-sdba)H2O]n·1.5nH2O (2), were assembled from metal salt precursors and 4,4-sulfonyldibenzoic acid (H2sdba). Both compounds were used as dopants for preparing hybrid biopolymer films based...
Lisboa pré-histórica: uma síntese da informação conhecida em 2020
Sousa, Ana Catarina; Costeira, Catarina; Costa, Ana Maria; Van Calker, Daniel; Cardoso, João LuísEste artigo resultou da fusão de duas comunicações distintas apresentadas na segunda sessão do ciclo de conferências Lisboa não é só Subterrânea — 25 anos depois de uma exposição, ocorrida no dia 4 de maio de 2019: «Depois de 1993: o que mudou na Pré-História de Lisboa», da autoria de um dos signatários (J. L. C.), e «Unir os pontos: uma abordagem geoespacial dos vestígios neolíticos e calcolíticos na cidade de...
Lisboa Pré-Histórica: uma síntese da informação conhecida em 2020
Sousa, Ana Catarina; Costeira, Catarina; Costa, Ana Maria; Calker, Daniel Van; Cardoso, João LuisEste artigo resultou da fusão de duas comunicações distintas apresentadas na segunda sessão do ciclo de conferências Lisboa não é só Subterrânea — 25 anos depois de uma exposição, ocorrida no dia 4 de maio de 2019: «Depois de 1993: o que mudou na Pré-História de Lisboa», da autoria de um dos signatários (J. L. C.), e «Unir os pontos: uma abordagem geoespacial dos vestígios neolíticos e calcolíticos na cidade de...
End-of-life management strategies of pharmaceuticals in Portuguese households
Veiga, Anabela; Sousa, Ana Catarina; Sousa, Cláudia; Oliveira, Manuel; Neto, BelmiraThe end of life of pharmaceutical products through environmentally unsafe routes is a growing concern in our society. However, the studies reported so far, apart from being limited in number, do not reflect the current management practices for the end-of-life management of pharmaceuticals. Published work lacks an in-depth analysis in focusing on the pharmaceutical waste in households. The present work focused o...
Allogenic synovia-derived mesenchymal stem cells for treatment of equine tendin...
Reis, Inês Leal; Lopes, Bruna; Sousa, Patrícia; Sousa, Ana Catarina; Branquinho, Mariana; Caseiro, Ana Rita; Pedrosa, Sílvia Santos; Rêma, AlexandraTendon and ligament injuries are frequent in sport horses and humans, and such injuries represent a significant therapeutic challenge. Tissue regeneration and function recovery are the paramount goals of tendon and ligament lesion management. Nowadays, several regenerative treatments are being developed, based on the use of stem cell and stem cell-based therapies. In the present study, the preparation of equine...
Sustainable synthesis, antiproliferative and acetylcholinesterase inhibition of...
Cabral, Rafaela G.; Viegas, Gonçalo; Pacheco, Rita; Sousa, Ana Catarina; Robalo, Maria PaulaThis work describes the design, sustainable synthesis, evaluation of electrochemical and biological properties against HepG2 cell lines, and AChE enzymes of different substituted derivatives of 1,4- and 1,2-naphthoquinones (NQ). A microwave-assisted protocol was optimized with success for the synthesis of the 2-substituted-1,4-NQ series and extended to the 4-substituted-1,2-NQ family, providing an alternative a...
A wide array of lignin-related phenolics are oxidized by an evolved bacterial d...
Silva, Diogo; Sousa, Ana Catarina; Robalo, Maria Paula; Martins, Lígia O.Lignin is the second most abundant natural polymer next to cellulose and by far the largest renewable source of aromatic compounds on the planet. Dye-decolourising peroxidases (DyPs) are biocatalysts with immense potential in lignocellulose biorefineries to valorize emerging lignin building blocks for environmentally friendly chemicals and materials. This work investigates the catalytic potential of the enginee...
Dextrin hydrogel loaded with a macroporous Bonelike® scaffold and dental pulp s...
Machado, A.; Pereira, Isabel; Pereira, José Eduardo; Maltez, Luís; Brandão, Ana; Alvites, Rui; Sousa, Ana Catarina; Branquinho, MarianaRegeneration of severe bone defects remains a challenge. A formulation of synthetic glass-reinforced hydroxyapatite bone substitute, Bonelike® Poro (BL®P), 250500 µm-diameter, with a dextrin-based hydrogel (HG), further loaded with human dental pulp stem cells (hDPSCs) with osteogenic differentiation ability, was tested for the management of critical-sized defects in an ovine model. Morphology, calcium release,...
Degradable copper(ii)-doped starch-based biopolymeric films with antibacterial ...
Trusau, K. I.; Jorge, Paula; Sousa, Ana Catarina; Fernandes, Tiago A.; André, Vânia; Kirillova, M. V.; Usevich, A. I.; Cerca, Nuno; Kirillov, A. M.The search for new bioactive molecules and sustainable materials to address antimicrobial resistance continues to be of significant attention in many research areas. In this work, new copper(II) coordination polymers and complexes containing ammonia and aromatic carboxylate ligands were self-assembled, characterized, and applied as bioactive dopants to produce starch-based biopolymeric films. The structures of ...