4 documents found, page 1 of 1
Sensitivity of different DNA extraction methods and PCR to detect resistance in...
Sevilha-Santos, Lais; Aquino, Danielle Costa; Hans Neto, Günter; Costa, Fabiano José Queiroz; Sousa, Carlos Augusto Felipe de; Morelo, Elaine FariaIntroduction: Antimicrobial resistance in leprosy is an emerging problem, and the quantitative impact of low bacilloscopic indexes (BIs) on the sensitivity of molecular tests is unknown. We aimed to evaluate the sensitivity of gene sequencing for the detection of mutations related to antimicrobial resistance in Mycobacterium leprae in patients with low BIs using an analytical model. Methods: Patients with lepro...
A comprehensive systematic review of leishmaniasis in patients undergoing drug-...
Kurizky, Patricia Shu; Marianelli, Fernanda Ferraço; Cesetti, Mariana Vicente; Damiani, Giovanni; Sampaio, Raimunda Nonata RibeiroImmunosuppression is an important risk factor for leishmaniasis. We assessed the clinical profile, geographic distribution and prevalence of leishmaniasis in patients undergoing immunosuppressive therapy for dermatological, rheumatological or gastroenterological autoimmune diseases. We identified relevant studies in PubMed, EMBASE, Scopus, Web of Science and LILACS on July 3rd, 2018. We included articles that r...
Pesquisa da resistência à ofloxacina e sua relação com a resposta clínica para ...
Sousa, Carlos Augusto Felipe deDissertação (mestrado)—Universidade de Brasília, Faculdade de Medicina, Programa de Pós-Graduação em Ciências Médicas, 2019.; Introdução: A hanseníase é uma doença infecciosa causada pelo Mycobacterium leprae e que resulta em importantes sequelas aos pacientes acometidos. O tratamento precoce é essencial para prevenção das incapacidades. Mecanismos moleculares e experimentais de resistência do M. leprae à oflox...
A comprehensive systematic review of leishmaniasis in patients undergoing drug-...
Kurizky, Patrícia Shu; Marianelli, Fernanda Ferraço; Cesetti, Mariana Vicente; Damiani, Giovanni; Sampaio, Raimunda Nonata RibeiroImmunosuppression is an important risk factor for leishmaniasis. We assessed the clinical profile, geographic distribution and prevalence of leishmaniasis in patients undergoing immunosuppressive therapy for dermatological, rheumatological or gastroenterological autoimmune diseases. We identified relevant studies in PubMed, EMBASE, Scopus, Web of Science and LILACS on July 3rd, 2018. We included articles that r...