Encontrados 5 documentos, a visualizar página 1 de 1
Corrigendum to Analysis of the mechanisms of action of isopentyl caffeate again...
Oliveira, Simone S. C.; Marques, Carine S. F.; Sousa, Damião P. de; Andrade, Luciana N.; Fricks, Alini T.; Jain, Sona; Branquinha, Marta H.Corrigendum to “Analysis of the mechanisms of action of isopentyl caffeate against Leishmania”. Biochimie 189 (2021) 158–167
Analysis of the mechanisms of action of isopentenyl caffeate against Leishmania
Oliveira, Simone S. C.; Marques, Carine S. F.; Sousa, Damião P. de; Andrade, Luciana N.; Fricks, Alini T.; Jain, Sona; Branquinha, Marta H.Leishmaniasis is a neglected parasitic disease for which the conventional treatment can be considered inefficient and extremely aggressive, generating several and severe side effects. Therefore, the discovery of new drug candidates is important for the improvement in the quality of life of patients. Previously, we reported the promising results of isopentyl caffeate (ICaf) against Leishmania chagasi (agent of v...
β-cyclodextrin/isopentyl caffeate inclusion complex: synthesis, characterizatio...
Marques, Carine S. F.; Barreto, Nathalia S.; Oliveira, Simone S. C. de; Santos, André L. S.; Branquinha, Marta H.; Sousa, Damião P. de; Castro, MayaraIsopentyl caffeate (ICaf) is a bioactive ester widely distributed in nature. Our patented work has shown promising results of this molecule against Leishmania. However, ICaf shows poor solubility, which limits its usage in clinical settings. In this work, we have proposed the development of an inclusion complex of ICaf in -cyclodextrin (-CD), with the aim to improve the drug solubility, and thus, its bioavailab...
Anti-inflammatory properties of rose oxide
Villarreal, Cristiane Flora; Melo, Flavielle Martins de; Nonato, Fabiana Regina; Santana, Daniele Gomes; Santos, Gisele Graça Leite dosTexto completo: acesso restrito. p. 779–784; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-04-29T15:14:49Z No. of bitstreams: 1 Cristiane Flora Villarreal.pdf: 514931 bytes, checksum: 14769cc91d175162ca0896db2847d9cc (MD5); Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2014-09-11T18:13:34Z (GMT) No. of bitstreams: 1 Cristiane Flora Villarreal.pdf: 514931 bytes, checks...
Antischistosomal activity of the terpene nerolidol
Silva, Marcos P.N.; Oliveira, George L.S.; Carvalho, Rusbene B.F. de; Sousa, Damião P. de; Freitas, Rivelilson M.; Pinto, Pedro L.S.; Moraes, Josué deSchistosomiasis is a neglected tropical disease that affects hundreds of millions of people worldwide. Since the treatment of this disease currently relies on a single drug, praziquantel, new and safe schistosomicidal agents are urgently required. Nerolidol, a sesquiterpene present in the essential oils of several plants, is found in many foods and was approved by the U.S. Food and Drug Administration. In this ...