47 documents found, page 1 of 5
Nursing Students' Learning in id.Care Research Initiation Programs
Sousa, Diana; Faria, José; Teixeira, Joana; Pinto, Maria do Rosário; Portela, Joana; Henriques, Helga RafaelIntroductionStudents' participation in research projects influences their professional development.1,2 It allows for the acquisition of knowledge and development of skills, the establishment of new attitudes that foster a research culture, and behavioral changes that enhance knowledge translation into care practices.1 Participation in research projects promotes positive attitudes towards research, facilitating ...
MicroRNA-665 and its potential role in drug response and survival outcomes in m...
Bergantim, Rui; Silva, Sara Peixoto da; Pinto, Vanessa; Pereira, Joana M.; Sousa, Diana; Trigo, Fernanda; Matthiesen, Rune; Guimarães, José E.Background: Multiple myeloma (MM) is a complex hematological malignancy with heterogeneous clinical and pathophysiological backgrounds that influence treatment responses and outcomes. Identifying biomarkers to predict drug response and guide treatment decisions, particularly regarding drug combinations, is essential to improve therapeutic efficacy and patient outcomes. This study explores the role of microRNAs ...
The differential diagnosis of adrenocortical tumors: systematic review of Ki-67...
Oliveira, Sofia B.; Machado, Mariana Q.; Sousa, Diana; Pereira, Sofia S.; Pignatelli, DuarteDistinguishing benign from malignant adrenocortical tumors (ACT) is not always easy, particularly for tumors with unclear malignant potential based on the histopathological features comprised of the Weiss score. Previous studies reported the potential utility of immunohistochemistry (IHC) markers to recognize malignancy, in particular the Insulin-like growth factor 2 (IGF2) and the proliferation marker, Ki-67. ...
Durable and breathable ZnO/graphene-coated fabrics for enhanced BQR protection
Ferreira, Tânia; Vale, A. Catarina; Gonçalves, Afonso; Pinto, Alexandra C.; Sousa, Diana; Guimarães, Humberto; Moreira, Inês P.; Silva, CarlosThis work developed a new strategy to create active protection against chemical, biological, radiological and nuclear (CBRN) threats, based on polyurethane-based coatings for outer (water and oil-repellency) and inner (CBRN protection) functionalization of fabric. The internal coatings were functionalized with varying concentrations of zinc oxide nanoparticles (ZnO) and/or graphene nanoplatelets (Gf) and carefu...
Nursing interventions to promote dyspnea self-management of complex chronic pat...
Henriques, Helga Rafael; Correia, Andreia; Santos, Tatiana; Faria, José; Sousa, Diana; Portela, Joana; Teixeira, JoanaObjectives: Chronic dyspnea, a distressing symptom in patients with complex chronic conditions, is linked to higher risks of mortality. This study aimed to identify nursing interventions that could improve self-management for complex chronic patients, thereby enhancing control over chronic dyspnea. The findings intend to guide nursing care strategies that promote self-management among this population. Methods: ...
Caracterização da pessoa que desenvolve úlcera por pressão em contexto de inter...
Mostardinha, António; Quitério, Carlos; Sousa, Diana; Martins, Isabel; Portela, Joana; Ferreira, NoéliaAs Úlceras Por Pressão (UPP) representam um problema de saúde, devido à sua incidência e pela morbilidade, mortalidade e risco de infeção associados. Num plano de prevenção de UPP, é fundamental conhecer as características individuais, de forma a minimizar os fatores de risco. Objetivou-se descrever as características da pessoa que desenvolveu UPP num centro hospitalar da região de Lisboa e Vale do Tejo, em 201...
Exposure to Obesogenic Environments during Perinatal Development Modulates Offs...
Sousa, Diana; Sá-Rocha, Mariana; Amaro, Andreia; Ferreira-Junior, Marcos Divino; Cavalcante, Keilah Valéria Naves; Monteiro-Alfredo, TamaehObesogenic environments such as Westernized diets, overnutrition, and exposure to glycation during gestation and lactation can alter peripheral neuroendocrine factors in offspring, predisposing for metabolic diseases in adulthood. Thus, we hypothesized that exposure to obesogenic environments during the perinatal period reprograms offspring energy balance mechanisms. Four rat obesogenic models were studied: mat...
The Bidirectional Relationship of NPY and Mitochondria in Energy Balance Regula...
Sousa, Diana; Lopes, Eduardo; Rosendo-Silva, Daniela; Matafome, PauloEnergy balance is regulated by several hormones and peptides, and neuropeptide Y is one of the most crucial in feeding and energy expenditure control. NPY is regulated by a series of peripheral nervous and humoral signals that are responsive to nutrient sensing, but its role in the energy balance is also intricately related to the energetic status, namely mitochondrial function. During fasting, mitochondrial dy...
As condições de trabalho e o stress ocupacional de profissionais de saúde duran...
Sousa, Diana; Sobral, Filipa; Morais, CatarinaEm março de 2020, a Organização Mundial de Saúde declarou a COVID-19 como pandemia. O seu surgimento e propagação contribuiu para aumentar os desafios existentes no quotidiano dos profissionais de saúde, impelindo o desenvolvimento de uma parceria entre o Serviço Nacional de Saúde e Privados para prestar uma resposta otimizada ao tratamento da doença, em Portugal. O stress ocupacional, traduzido no medo e preoc...
Polymeric biomaterials for wound healing
Oliveira, Cristiana; Sousa, Diana; Teixeira, J. A.; Santos, Pedro Miguel Ferreira; Botelho, C. M.Skin indicates a person’s state of health and is so important that it influences a person’s emotional and psychological behavior. In this context, the effective treatment of wounds is a major concern, since several conventional wound healing materials have not been able to provide adequate healing, often leading to scar formation. Hence, the development of innovative biomaterials for wound healing is essential....