Anterior cruciate ligament (ACL) injuries pose significant challenges, driving the need for innovative repair strategies. Tissue engineering (TE) has emerged as a promising field for ACL injuries. Wet spinning is a filament production technique that enables precise control over filament alignment, diameter, and porosity, making it suitable for developing new scaffolds for ACL injuries. This study develops fibro...
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Pathogen genome sequencing during epidemics enhances our ability to identify and understand suspected clusters and investigate their relationships. Here, we combine genomic and epidemiological data of the 2022 mpox outbreak to better understand early viral spread, diversification and transmission dynamics. By sequencing 52% of the confirmed cases in Portugal, we identified the mpox virus sublineages with the hi...
[Excerpt] Introduction Tendon and ligament injuries have a major impact on joint mobility and musculoskeletal performance. Current treatments frequently fall short of expectations, necessitating the development of artificial fibrous scaffolds that closely resemble native tissue. Wet polymeric nanofibers, particularly those based on poly(-caprolactone) (PCL), have shown promise in terms of biocompatibility, biod...
Late-onset pharyngeal perforation is a rare complication of anterior cervical spine osteosynthesis. Clinical presentation is variable and may led to serious complications. We present a 49-year-old male patient with a six-week history of throat pain and foreign body sensation. He had a previous documented odontoid fracture treated with osteosynthesis with an interf ragmentary screw performed 30 years ago. A scre...
Pathogen genome sequencing during epidemics enhances our ability to identify and understand suspected clusters and investigate their relationships. Here, we combine genomic and epidemiological data of the 2022 mpox outbreak to better understand early viral spread, diversification and transmission dynamics. By sequencing 52% of the confirmed cases in Portugal, we identified the mpox virus sublineages with the hi...
Giant cell tumors (GCTs) of the ischium are rare and often diagnosed at an advanced stage. In fact, there is no defined treatment algorithm to treat this lesion. We present two case reports of Campanacci's stage three ischiopubic GCT confirmed with biopsy. They were effectively treated with excision of the ischiopubic ramus, aggressive curettage, drilling, and phenolization at the margins. The surgery was perfo...
Introduction and Geological context The Iberian Massif is the most southwestern domain of European Variscides, displaying an internal organization that allows to identify several palaeogeographic zones, among which the Ossa-Morena Zone (OMZ) that is included in the hinterland domains of this Massif. The Carboniferous sedimentation in the hinterland is restricted to small basins, controlled by the tectonic setti...