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New pharmacological targets against COVID-19: the use of interferons for activa...
Mainardo Rodrigues Bezerra, Lucas; Carvalho Neto, Pedro Oliveira; Silva, Fernando José de Morais; Ramos, Madelyne Alice Brito; Cardoso, Ana Maria SantosSARS-CoV-2 virus, cause of COVID-19 disease, was described at first in Wuhan (China) December 2019, infecting more than 170 million people. During viral infection, innate immune system initially acts with cell signaling leading to the production and release of pro-inflammatory cytokines, mostly characterized by low levels of interferons (IFNs), which stimulate the expression of genes that contribute to the disp...
Date: 2021
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Origin: Oasisbr