This study examined how lighting conditions (White, or a combination of Red + Blue LEDs; and supplemental UV-C: 0, 1 or 3 applications) and cultivars (Daikon, Red Rambo) affected the colour, total phenolics content, antioxidant activity and individual polyphenols of radish microgreens (Raphanus sativus L.) in a sustainable vertical farming system, as well as the implications for polyphenolic intake, connecting ...
Brassica microgreens are rich in phytochemicals and are attractive crops for controlled vertical farming systems where the light spectrum can be precisely manipulated. Understanding the effects of pre-harvest hormetic UV-C light doses on plant composition and growth parameters represents a novel and largely unexplored area for precision agriculture and nutrition. Therefore, the objective of this work was to inv...
The integration of foodomics data to explain the impact of diet on health requires a precise knowledge of nutrients composition of complex meals. This work assesses the adequacy of two food composition databases (FCDBs) for calculation of nutritional composition of whole meals, compared to the golden standard lab chemical analyses and search for predictive models to overcome some limitations of FCDBs. Six meals...
HIV/AIDS stands as a global burden, and vaginal microbicides constitute a promising strategy for topical pre-exposure prophylaxis. Preceding the development of a microbicide containing tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC), in silico and in vitro studies were performed to evaluate the physicochemical characteristics of both drugs, and to study their biophysical impact in lipid model system...
Haemophilia A is a hereditary bleeding disorder, which has been considered rare and chronic. The burden of this disease in Portugal remains unknown. The aim of this study was to estimate the annualized cost and health burden of haemophilia A in Portugal.
Gangrenous cystitis is a rare condition, there are no typical symptoms or clinical findings, which hampers diagnosis and may worsen the prognosis. The authors report the case of a diabetic male patient, hospitalized because of poor general condition, dehydration and diffuse abdominal pain. The diagnosis was made by typical pelvic CT findings. Medical treatment must be intensive and begun as soon as possible. As...