3 documents found, page 1 of 1
TNF-alpha expression, evaluation of collagen, and TUNEL of Matricaria recutita ...
Oliveira, Bruna Vasconcelos; Silva, Paulo Goberlânio de Barros; Nojosa, Jacqueline Santiago; Brizeno, Luiz André Cavalcante; Ferreira, Jamile MagalhãesOBJECTIVES: Characterize the cell profile and immunostaining of proinflammatory markers in an experimental model of bisphosphonate-related osteonecrosis of the jaw (BRONJ). MATERIALS AND METHODS: Male Wistar rats (n = 6– 7) were treated chronically with saline solution or zoledronic acid (ZA) at 0.04, 0.20, and 1.00 mg kg 1 (1.4 3 10 7, 6.9 3 10 6, and 3.4 3 10 5 mol kg 1), and subsequently, the first left inferio...
Chronic treatment with zoledronic acid increases inflammatory markers in period...
Silva, Paulo Goberlânio de Barros; Ferreira Junior, Antonio Ernando Carlos; Oliveira, Camila Carvalho de Oliveira; Brizeno, Luiz André CavalcanteBackground: Bisphosphonates (BF) rise proinflammatory markers and irreversibly bind to bone. Chronically, BF can lead to an inflammatory status and can increase the local oxidative stress in periodontium. Therefore, the objective of this study was to evaluate whether the chronic infusion of Zoledronic Acid (ZA) increases inflam- matory markers in periodontium of rats. Methods and results: Chronically, infusion ...
Evaluation of oral conditions in patients with neurodegenerative diseases treat...
Frota, Bruna Marjorie Dias; Holanda, Sarah Nascimento; Sousa, Fabrício Bitú; Alves, Ana Paula Negreiros NunesObjective To compare the general clinical conditions and oral alterations, and also evaluate the prosthesis, in subjects diagnosed with Alzheimer's disease (AD) or Parkinson's disease (PD), attended at two geriatric centers in the city of Fortaleza - Ceará. Methods 70 patients were analyzed (between 57 to 91 years) with AD and PD, through evaluation of neurological medical records and oral clinical examination....