7 documents found, page 1 of 1
Cognitive deficits, social support, depression and quality of life of post-stro...
Sousa, Flávia; Rocha, Vânia; Estima, Clara; Castro, São Luís; Guerra, Marina PristaA stroke is a life-threatening event which has physical, emotional and cognitive consequences. Thisstudy aimed to identify differences between participants who suffered a stroke and healthy controls,concerning cognitive performance, depressive symptoms, social support and quality of life; to examinethe associations between these variables among participants who suffered a stroke; and to identify thevariables th...
Cognitive deficits, social support, depression and quality of life of post-stro...
Sousa, Flávia; Rocha, Vânia; Estima, Clara; Castro, São Luís; Guerra, Marina PristaAbstract: A stroke is a life-threatening event which has physical, emotional and cognitive consequences. This study aimed to identify differences between participants who suffered a stroke and healthy controls, concerning cognitive performance, depressive symptoms, social support and quality of life; to examine the associations between these variables among participants who suffered a stroke; and to identify th...
Alginate-Based Delivery Systems for Bevacizumab Local Therapy: In Vitro Structu...
Ferreira, Natália Noronha [UNESP]; Caetano, Bruno Leonardo [UNESP]; Boni, Fernanda Isadora [UNESP]; Sousa, Flávia; Magnani, Marina [UNESP]Made available in DSpace on 2019-10-06T15:30:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-04-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Fundació Catalana de Trasplantament; European Regional Development Fund; Alginate-based polyelectrolyte complexes (PECs) and hydrogel were engineered as platforms for loca...
Extraction and characterisation of cellulose nanocrystals from pineapple peel
Madureira, Ana Raquel; Atatoprak, Tugba; Çabuk, Duygu; Sousa, Flávia; Pullar, Robert C.; Pintado, ManuelaThe potential of pineapple peel as a source of cellulose nanocrystals was evaluated. Peels skin from fresh-cut fruit was used as raw material. These residues were puri ed to remove pigments, lipids and hemicellulose, and a bleaching process for deligni cation was carried out for 4-6 h. All resulting products were characterised for their lignin, hemicellulose, cellulose and ash contents using standard techniques...
Incorporation of beads into oral films for buccal and oral delivery of bioactiv...
Castro, Pedro M.; Sousa, Flávia; Magalhães, Rui; Ruiz-Henestrosaf, Victor Manuel Pizones; Pilosoff, Ana M.R.; Madureira, Ana Raquel; Sarmento, BrunoThe association of alginate beads and guar-gum films in a single delivery system was idealized to promote a more effective buccal and oral delivery of bioactive molecules. A response surface method (experimental design approach) was performed to obtain optimal formulations of alginate beads to be incorporated into guar gum oral films as combined buccal and oral delivery systems for caffeine delivery. The combin...
Oral films as breakthrough tools for oral delivery of proteins/peptides
Castro, Pedro M.; Fonte, Pedro; Sousa, Flávia; Madureira, Ana Raquel; Sarmento, Bruno; Pintado, Manuela E.Therapeutic proteins and peptides demonstrate unique, peerless, pharmacological characteristics such as high specificity to receptors and superior biological mimicking of physiological mechanisms, resulting in a better therapeutic index compared to conventional chemical-derived drugs. However, proteins also present inherent bioavailability limitations. Thus, this paper proposes several effective tools to improv...
Relatório de Projeto – ANÁLISE DE CHEIAS EM AMBIENTE SIG NA REGIÃO DO PESO DA R...
Sousa, FláviaTodos os anos na região do Peso da Régua ocorrem cheias que provocam grandes estragos, devido a esse fenómeno natural, será realizado um estudo com recurso aos Sistemas de Informação Geográfica (SIG) com vista a analizar o risco de inundação no Rio Douro. Devido aos estragos provocados, realizou-se este projeto como forma de analisar este fenómeno. Numa primeira fase procedeu-se ao estudo para determinar os fat...