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Pseudoboehmite as a drug delivery system for acyclovir

Peres, RM; Sousa, JML; Oliveira, MO; Rossi, MV; Oliveira, RR; Lima, NB; Bernussi, A; Warzywoda, J; Sarmento, B; Munhoz, AH

Herpes simplex virus is among the most prevalent sexually transmitted infections. Acyclovir is a potent, selective inhibitor of herpes viruses and it is indicated for the treatment and management of recurrent cold sores on the lips and face, genital herpes, among other diseases. The problem of the oral bioavailability of acyclovir is limited because of the low permeability across the gastrointestinal membrane. ...

Date: 2021   |   Origin: Repositório Aberto da Universidade do Porto
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