7 documents found, page 1 of 1

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Early Mobilization Decision after an Acute Ischemic Stroke: Protocol for an Umb...

Fernandes, Catarina; Sousa, João André; Bernardo-Castro, Sara; Silva, Fernando; Donato, Helena; Sargento-Freitas, João

Introduction: Stroke is considered one of the greatest public health challenges worldwide, with the ischemic subtype being the most prevalent. Various acute stroke clinical guidelines recommend early rehabilitation interventions, including very early mobilization. However, despite the studies conducted in recent years regarding when to initiate mobilization after an acute stroke, there are few systematic and pe...

Date: 2024   |   Origin: Acta Médica Portuguesa

In the Wink of an Eye: Revisiting Marcus Gunn Syndrome

Sousa, João André; Palavra, Filipe

Date: 2024   |   Origin: SINAPSE

Reconsidering the role of blood-brain barrier in Alzheimer's disease: From deli...

Sousa, João André; Bernardes, Catarina; Bernardo-Castro, Sara; Lino, Miguel; Albino, Inês; Ferreira, Lino; Brás, José; Guerreiro, Rita

The existence of a selective blood-brain barrier (BBB) and neurovascular coupling are two unique central nervous system vasculature features that result in an intimate relationship between neurons, glia, and blood vessels. This leads to a significant pathophysiological overlap between neurodegenerative and cerebrovascular diseases. Alzheimer's disease (AD) is the most prevalent neurodegenerative disease whose p...


Therapeutic Approaches for Stroke: A Biomaterials Perspective

Rodrigues, Artur Filipe; Rebelo, Catarina; Reis, Tiago; Sousa, João André; Pinho, Sónia L. C.; Sargento-Freitas, João; Peça, João; Ferreira, Lino

Stroke is a leading cause of death worldwide and poses significant societal and healthcare challenges due to functional impairment of the brain. In order to fully restore brain function, innovative approaches have aimed to regenerate the injured tissue and to restore neuronal circuitry. In the last 5 years, stem cells have been consistently explored in clinical trials for tissue regeneration. Recent technologic...


Therapeutic Nanoparticles for the Different Phases of Ischemic Stroke

Bernardo-Castro, Sara; Albino, Inês; Barrera-Sandoval, Ángela María; Tomatis, Francesca; Sousa, João André; Martins, Emanuel; Simões, Susana

Stroke represents the second leading cause of mortality and morbidity worldwide. Ischemic strokes are the most prevalent type of stroke, and they are characterized by a series of pathological events prompted by an arterial occlusion that leads to a heterogeneous pathophysiological response through different hemodynamic phases, namely the hyperacute, acute, subacute, and chronic phases. Stroke treatment is highl...



Letter to the Editor about the Article “Barrett or Barré?: The Need to End a Co...

Reis Carneiro, Diogo; Sousa, João André

N/a.; N/a.

Date: 2021   |   Origin: Acta Médica Portuguesa

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