27 documents found, page 1 of 3
Neurological lesions in cervids: a study in Portugal
Pires, Maria A.; Macêdo, J.; Seixas, Fernanda; Gama, Adelina; Alves, Anabela; Pinto, Maria de Lurdes; Pires, Isabel; Matos, Ana Cristina; Figueira, LuisBrain samples were collected within the project "CWD Risk in Portugal", profiOng the infecOous diseases epidemiological surveillance and screening of chronic wasOng disease (CWD) during cervids hunts. The literature on wild animals´ neuropathological lesions is scarse. This work aims to describe the neuropathological findings in samples collected in deer hunted in Portugal.
Estimating sequence diversity of prion protein gene (PRNP) in Portuguese popula...
Pereira, Jorge C.; Gonçalves-Anjo, Nuno; Orge, Leonor; Pires, Maria dos Anjos; Rocha, Sara; Figueira, Luís; Matos, Ana Cristina; Silva, JoãoAmong the transmissible spongiform encephalopathies (TSEs), chronic wasting disease (CWD) in cervids is now a rising concern in wildlife within Europe, after the detection of the first case in Norway in 2016, in a wild reindeer and until June 2022 a total of 34 cases were described in Norway, Sweden and Finland. The definite diagnosis is post-mortem, performed in target areas of the brain and lymph nodes. Sampl...
Boosting caffeic acid performance as antioxidant and monoamine oxidase B/catech...
Chavarria, Daniel; Benfeito, Sofia; Soares, Pedro; Lima, Carla; Garrido, Jorge; Serrão, Paula; Soares-da-Silva, Patrício; Remião, FernandoIncreased oxidative stress (OS) and depletion of nigrostriatal dopamine (DA) are closely linked to the neurodegeneration observed in Parkinson’s Disease (PD). Caffeic acid (CA)-based antioxidants were developed, and their inhibitory activities towards monoamine oxidases (MAOs) and catechol O-methyltransferases (COMT) were screened. The results showed that the incorporation of an extra double bond maintained or ...
Proteomic analysis capsule synthesis and redox mechanisms in the intracellular ...
Eto, Silas Fernandes; Fernandes, Dayanne Carla; Baldassi, Amanda Cristina [UNESP]; Balbuena, Thiago Santana [UNESP]; da Costa Alecrim, João VictorMade available in DSpace on 2022-04-28T19:44:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Group B Streptococcus (GBS) causes meningitis in neonates and Nile tilapia (Oreochromis niloticus). The molecular mechanisms regulating the intracellular survival of this pathogen in the host cell are complex and crucial for the progression ...
Chronic wasting disease risk assessment in Portugal: results and future work.
Pires, Maria dos Anjos; Torres, Juan Maria; Pereira, Jorge C.; Gonçalves-Anjo, Nuno; Bastos, Estela; Matos, Ana Cristina; Gama, Adelina; Alves, AnabelaChronic wasting disease risk assessment in Portugal: results and future work.
Chronic wasting disease (CWD) risk assessment in Portugal : The genetic approac...
Pereira, Jorge C.; Gonçalves-Anjo, Nuno; Bastos, Estela; Rocha, Sara; Figueira, Luís; Matos, Ana Cristina; Machado, Carla; Silva, João; Mendonça, PaulaAmong the transmissible spongiform encephalopathies (TSEs), chronic wasting disease (CWD) in cervids is now the rising concern in wildlife within Europe, after the first case was detected in Norway in 2016, in a wild reindeer and until October 2021, a total of 34 cases were described in Norway, Sweden and Finland.
Analysis of sequence variability of prion protein gene (PRNP) in Portuguese cer...
Pereira, Jorge C.; Machado, Ana; Gonçalves-Anjo, Nuno; Bastos, Estela; Orge, Leonor; Rocha, Sara; Figueira, Luís; Matos, Ana Cristina; Silva, JoãoTransmissible Spongiform Encephalopathy (TSE) or prion diseases are a family of neurodegenerative diseases caused by lethal infectious pathogens called Prions. Among the transmissible spongiform encephalopathies (TSEs), chronic wasting disease (CWD) in cervids is now the rising concern in wildlife within Europe, after the first case was detected in Norway in 2016, in a wild reindeer and until October 2021, a to...
Chronic wasting disease risk assessment in Portugal: analysis of variability an...
Gonçalves-Anjo, Nuno; Pereira, Jorge C.; Machado, Ana; Saianda, Mafalda; Bastos, Estela; Orge, Leonor; Rocha, Sara; Figueira, Luís; Matos, Ana CristinaAmong the Transmissible Spongiform Encephalopathies, Chronic Wasting Disease (CWD) in cervids is now the rising concern in wildlife within Europe after the first case detected in Norway in 2016. CWD shows a notable horizontal transmission, affecting both free-ranging and captive cervids. Furthermore, several genetic variants in the Prion Protein (PRNP) gene coding sequence of the cervid were identified, which i...
Determining prion protein gene (PRNP) genetic variability in portuguese cervida...
Pereira, Jorge C.; Machado, Ana; Saianda, Mafalda; Gonçalves-Anjo, Nuno; Bastos, Estela; Orge, Leonor; Rocha, Sara; Figueira, Luís; Matos, Ana CristinaThe chronic wasting disease (CWD) in cervids is now a rising concern in wildlife within Europe, since the first case detected in Norway in 2016, 40 more appear until May of 2022, in Norway, Sweden and Finland. The unclear origin of these new European cases and the risk that CWD poses to cohabiting ani-mals or more importantly to humans is largely unknown, is very important for the establishment of risk assessme...
Are Western Iberian roe deer populations hotspots of genetic diversity?
Pereira, Jorge C.; Machado, Ana; Saianda, Mafalda; Gonçalves-Anjo, Nuno; Bastos, Estela; Orge, Leonor; Rocha, Sara; Figueira, Luís; Matos, Ana CristinaGiven its geographic isolation, and after the last glaciation, the Iberian Peninsula, become a sanctuary of plants and animal’s diversification, being considered a hotspot of genetic diversity specially for mammal species. The roe deer (Capreolus capreolus - CCR), an herbivore ungulate, has a widespread geographical distribution which extends from the Iberian Peninsula to the north of Scandinavia, being found a...