3 documents found, page 1 of 1
Bothrops pauloensis snake venom-derived Asp-49 and Lys-49 phospholipases A2 med...
Marinho, Aline Diogo; Silveira, João Alison de Moraes; Chaves Filho, Adriano José Maia; Jorge, Antônio Rafael Coelho; Nogueira Júnior, Francisco AssisMade available in DSpace on 2021-06-25T11:09:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-30; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); University of Cambridge; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The envenomation caused by the Bothrops pauloensis snake leads to severe loca...
Dual effect of silymarin on experimental non-alcoholic steatohepatitis induced ...
Assis-Júnior, Eudmar Marcolino; Melo, Anielle Torres; Pereira, Venúcia Bruna Magalhães; Wong, Deysi Viviana Tenazoa; Sousa, Nathalia Ribeiro PinhoIrinotecan-based regimens are commonly used for treatment of colorectal cancer, which is limited by mucositis and non-alcoholic steatohepatitis (NASH). Silymarin (SIL) prevents fatty liver disease in the clinical setting and in models of liver damage induced chemically. This study investigated the possible effect of SIL on irinotecan (IRI)-induced NASH. Swiss female mice were injected with saline (SAL 5 ml/kg i...
Novo modelo de mucosite intestinal induzida pela associação de irinotecano e 5-...
Pereira, Venúcia Bruna MagalhãesIntroduction: Intestinal mucositis is a common side effect of anticancer regimens for first-line treatment of colorectal cancer. Among such drugs are irinotecan and 5-FU used in combination. Many studies have been conducted on the pathogenesis of MI. However, further investigations are necessary, because the course of MI may vary according to the drug regimen and employees. Then aimed to develop a new experimen...