37 documents found, page 1 of 4
Assessment of functional physical fitness and functional dependence after a phy...
Sousa, Mário; Sousa, Mário; Tomás, Maria TeresaIntroduction – The functional physical fitness (FpF) level in patients admitted to Medium Duration and Rehabilitation Integrated Continuous Care Units (MDR-ICCU) and the functional limitations associated with these patients remain unknown. Objective – To assess the FpF of patients admitted to MDR-ICCU after completing a physiotherapy program and compare the FpF results between patients with and without a stroke...
A systematic review of bleomycin-induced gonadotoxicity: Mechanistic implicatio...
Almeida, Ana Lobo de; Fortuna, Ana; Sousa, Mário; Sá, RosáliaLong-term cancer treatment complications in men include testicular dysfunction and infertility. Although various chemotherapies have been studied, there is limited evidence on their effects, especially for bleomycin. Despite its known lung toxicity, bleomycin's impact on male reproductive health is not well-researched. This systematic review aimed to evaluate bleomycin's effects on testicular function and ferti...
Using peptide nucleic acid fluorescence in situ hybridization (PNA-FISH) to det...
Oliveira, Ricardo Bruno Costa; Barbosa, Ana; Sousa, Mário; Azevedo, Nuno Filipe; Cerqueira, Laura; Almeida, Carina Manuela FernandesFoodborne diseases have a considerable negative impact on socioeconomic development globally and are an important cause of morbidity and mortality. Among the foodborne bacterial pathogens, Campylobacter spp. is recognized as the leading cause of foodborne illness. Fluorescent in situ hybridization using nucleic acid mimics (NAM-FISH) as probes, in particular peptide nucleic acid (PNA) probes, is a molecular tec...
Validation of a peptide nucleic acid fluorescence in situ hybridization for the...
Sousa, Mário; Rocha, Rui; Araújo, Daniela; Castro, Joana; Barbosa, Ana; Azevedo, Nuno F.; Cerqueira, Laura; Almeida, Carina Manuela FernandesSalmonella is a Gram-negative flagellated rod-shaped bacterium that is one of the most important etiological agents in bacterial foodborne diseases [1,2]. Despite human salmonellosis generally presenting as a self-limiting episode of enterocolitis, the infection can degenerate into chronic and debilitating conditions [2]. To diagnose a Salmonella infection, standard cultural methods are routinely used, which im...
Impact of different levels of information presentation on user experience: a Ca...
Silva, André; Sousa, Carlos; Paulino, Dennis; Sousa, Mário; Melo, Miguel Ângelo Correia de; Bessa, Maximino Esteves CorreiaUser experience can be affected by the amount and intensity of information presented. Four scenarios were developed to assess the insertion of information elements (chronometer and hint system) and tested with 37 users to find out if they affected the user's sense of presence and symptoms of cybersickness. In order to instruct users and using virtual reality using the Unity 3D game engine, we created a virtual ...
New evidences of ubiquitin-proteasome system activity in human sperm
Silva, Joana Vieira; Santiago, Joana; Sousa, Mário; Oliveira, Pedro F; Fardilha, MargaridaSem resumo disponível.
AVALIAÇÃO DA VIABILIDADE ECONÓMICA DA ENERGIA SOLAR FOTOVOLTAICA: ESTUDO DE CAS...
Sousa, Mário; Morgado, SóniaA escolha de uma fonte de energia é expectável em face da consciencialização ambiental e dos custos orçamentais da polícia. O artigo examina a sustentabilidade económica da implementação da energia solar fotovoltaica nas esquadras da polícia, com a definição do custo, payback, retorno do investimento, valor atual líquido, taxa interna de rentabilidade e viabilidade do investimento. A par da análise económica, u...
Metabolic dynamics of human Sertoli cells are differentially modulated by physi...
Martins, Ana D.; Monteiro, Mariana P.; Silva, Branca M.; Barros, Alberto; Sousa, Mário; Carvalho, Rui A.; Oliveira, P.F.; Alves, Marco G.Obesity incidence has pandemic proportions and is expected to increase even further. Glucagon-like peptide-1 (GLP-1) based therapies are well-established pharmacological resources for obesity treatment. GLP-1 regulates energy and glucose homeostasis, which are also crucial for spermatogenesis. Herein, we studied the GLP-1 effects in human Sertoli cells (hSCs) metabolism and mitochondrial function. hSCs were cul...
L-Theanine promotes cultured human Sertoli cells proliferation and modulates gl...
Dias, T. R.; Bernardino, Raquel; Alves, Marco G; Silva, Joaquina; Barros, Alberto; Sousa, Mário; Casal, Susana; Silva, Branca M.; Oliveira, P.F.L-Theanine is the major free amino acid present in tea (Camellia sinensis L.). The effects of several tea constituents on male reproduction have been investigated, but L-theanine has been overlooked. Sertoli cells (SCs) are essential for the physical and nutritional support of germ cells. In this study, we aimed to investigate the ability of L-theanine to modulate important mechanisms of human SCs (hSCs) metabo...
Impulsivity across reactive, proactive and cognitive domains in Parkinson's dis...
Canário, Nádia; Sousa, Mário; Moreira, Fradique; Duarte, Isabel Catarina; Oliveira, Francisco; Januário, Cristina; Castelo-Branco, MiguelImpulse control disorders (ICD) may occur in Parkinson's disease (PD) although it remains to be understood if such deficits may occur even in the absence of a formal ICD diagnosis. Moreover, studies addressing simultaneously distinct neurobehavioral domains, such as cognitive, proactive and reactive motor impulsivity, are still lacking. Here, we aimed to investigate if reactive, proactive and cognitive impulsiv...